{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T09:29:12Z","timestamp":1768296552045,"version":"3.49.0"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T00:00:00Z","timestamp":1255564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>Scrub typhus (<jats:italic>Orientia tsutsugamushi<\/jats:italic>) is a Gram\u2010negative rickettsial disease in parts of Asia, transmitted from wild rodents to human by mites. This is a case report of scrub typhus contraction in an acute leukemia patient by transfusion of peripheral blood stem cells collected during the incubation period. Although human\u2010to\u2010human transmission of scrub typhus by needle\u2010stick injury or transplacental transmission has previously been reported, this is the first case confirmed by polymerase chain reaction (PCR) and DNA sequencing. This type of incident shows the need to heighten awareness of the threat of rickettsial agents in transfused blood. Nested PCR is a useful diagnostic method to confirm the diagnosis during incubation period and in the early phase of disease, especially for immunocompromised patients.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2009.02442.x","type":"journal-article","created":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T14:54:06Z","timestamp":1255618446000},"page":"467-470","source":"Crossref","is-referenced-by-count":5,"title":["Scrub typhus induced by peripheral blood stem cell transplantation in the immunocompromised patient: diagnostic usefulness of nested polymerase chain reaction"],"prefix":"10.1111","volume":"50","author":[{"given":"Seung\u2010Ji","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung\u2010Hwa","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sook\u2010In","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee Chang","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Young","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Sook","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeoung Joon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong\u2010Hee","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"crossref","first-page":"542","DOI":"10.4269\/ajtmh.2006.75.542","article-title":"Usefulness of nested PCR for the diagnosis of scrub typhus in clinical practice: a prospective study","volume":"75","author":"Kim DM","year":"2006","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365549609037929"},{"key":"e_1_2_5_4_2","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1542\/peds.89.5.965","article-title":"Neonatal scrub typhus: a case report","volume":"89","author":"Wang CL","year":"1992","journal-title":"Pediatrics"},{"key":"e_1_2_5_5_2","first-page":"198","article-title":"Haematological studies in scrub typhus","volume":"10","author":"Fang RC","year":"1974","journal-title":"Asian J Med"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704848"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1992.tb02118.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1998.38798346638.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/146.6.811"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2006.00941.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01798.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2005.12.003"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1537-2995.2009.02442.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1537-2995.2009.02442.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T19:10:19Z","timestamp":1697310619000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1537-2995.2009.02442.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.1111\/j.1537-2995.2009.02442.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1537-2995.2009.02442.x","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}