{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:37:26Z","timestamp":1790901446862,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2011,3,10]],"date-time":"2011-03-10T00:00:00Z","timestamp":1299715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Transfusion\u2010transmitted leishmaniasis is an increasing problem in areas where visceral and cutaneous leishmaniases are endemic.<\/jats:p><jats:p><jats:bold>CASE REPORT:<\/jats:bold> This article reports a case of transfusion\u2010transmitted fatal visceral leishmaniasis (VL) caused by <jats:italic>Leishmania (Leishmania) mexicana<\/jats:italic> in a 42\u2010year\u2010old male resident of northwestern Colombia who after developing a terminal renal failure due to lupus nephritis received a renal transplant and multiple transfusions.<\/jats:p><jats:p><jats:bold>RESULTS:<\/jats:bold> Multiple intracellular <jats:italic>Leishmania<\/jats:italic> amastigotes were demonstrated in both renal biopsy and marrow aspirates. Cultures of the parasite were obtained in NNN medium and the identification of the species was done both by direct immunofluorescence and polymerase chain reaction\u2013restriction fragment length polymorphism.<\/jats:p><jats:p><jats:bold>CONCLUSIONS:<\/jats:bold> This is the first report of a VL case produced by <jats:italic>L. (L.) mexicana<\/jats:italic> in Colombia, which usually is a dermotropic species. Our report suggests that although leishmaniasis is transmitted by the bite of phlebotomine sand flies, <jats:italic>Leishmania<\/jats:italic> parasite may be transmitted by blood transfusion, complicating the clinical course of organ transplant and being fatal.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2011.03092.x","type":"journal-article","created":{"date-parts":[[2011,3,10]],"date-time":"2011-03-10T14:29:38Z","timestamp":1299767378000},"page":"1919-1923","source":"Crossref","is-referenced-by-count":22,"title":["Transfusion\u2010transmitted visceral leishmaniasis caused by <i>Leishmania (Leishmania) mexicana<\/i> in an immunocompromised patient: a case report"],"prefix":"10.1111","volume":"51","author":[{"given":"Laureano","family":"Mestra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Lopez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Robledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos E.","family":"Muskus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rub\u00e9n S.","family":"Nicholls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iv\u00e1n Dar\u00edo","family":"V\u00e9lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,10]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2003.09.009"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.181"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2005.06.025"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762000000500022"},{"key":"e_1_2_7_6_2","doi-asserted-by":"crossref","first-page":"206","DOI":"10.4269\/ajtmh.1990.42.206","article-title":"Distribution and etiology of leishmaniasis in Colombia","volume":"42","author":"Corredor A","year":"1990","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761999000300001"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.v5i3-4.1909"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.v26i1.1517"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2006.02.033"},{"key":"e_1_2_7_11_2","doi-asserted-by":"crossref","first-page":"926","DOI":"10.4049\/jimmunol.129.3.926","article-title":"Monoclonal antibodies that distinguish subspecies of Leishmania braziliensis","volume":"129","author":"McMahon\u2010Pratt D","year":"1982","journal-title":"J Immunol"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2005.07.003"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00061-07"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70043-4"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21538"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2005.06.002"},{"key":"e_1_2_7_17_2","unstructured":"World Health Organization.The disease and its epidemiology.2010. 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