{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T11:23:46Z","timestamp":1783077826493,"version":"3.54.6"},"reference-count":8,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2011,6,9]],"date-time":"2011-06-09T00:00:00Z","timestamp":1307577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Anti\u2010IH is usually a clinically insignificant antibody that may complicate a serologic workup. However, it can occasionally cause hemolysis. We report a rare case of acute hemolysis caused by anti\u2010IH.<\/jats:p><jats:p><jats:bold>CASE REPORT:<\/jats:bold> A 60\u2010year\u2010old man with a long history of chronic myelomonocytic leukemia and anemia, blood group A, D+ was found to have an unidentified antibody on serologic workup. He received an A, D+ red blood cell (RBC) unit that was crossmatch compatible by immunoglobulin G indirect antiglobulin test and then experienced an acute hemolytic transfusion reaction with fever, hemoglobinuria, and acute renal failure. The antibody was later identified as an anti\u2010IH with a wide thermal amplitude. The transfused RBCs were later typed as A<jats:sub>2<\/jats:sub>. The patient was subsequently typed as an A<jats:sub>1<\/jats:sub> individual. The patient recovered completely from the effects of this reaction and was transfused with A<jats:sub>1<\/jats:sub> RBCs over the next few days with no adverse effect.<\/jats:p><jats:p><jats:bold>CONCLUSION:<\/jats:bold> Anti\u2010IH, which is usually clinically insignificant and often found in A<jats:sub>1<\/jats:sub>, B, and A<jats:sub>1<\/jats:sub>B individuals, can, on rare occasions, cause acute hemolytic transfusion reactions, especially when an A<jats:sub>2<\/jats:sub> unit is transfused to an A<jats:sub>1<\/jats:sub> patient.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2011.03209.x","type":"journal-article","created":{"date-parts":[[2011,6,10]],"date-time":"2011-06-10T00:43:19Z","timestamp":1307666599000},"page":"2676-2678","source":"Crossref","is-referenced-by-count":15,"title":["Hemolytic transfusion reaction due to anti\u2010IH"],"prefix":"10.1111","volume":"51","author":[{"given":"Mehraboon S.","family":"Irani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,6,9]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"159","article-title":"The detection of a product of the blood group O gene and the relationship of the so\u2010called O\u2010substance to the agglutinogens A and B","volume":"29","author":"Morgan WT","year":"1948","journal-title":"Br J Exp Pathol"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1964.tb03309.x"},{"key":"e_1_2_6_4_2","volume-title":"Blood transfusion in clinical medicine","author":"Mollison PL","year":"1997"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2000.40070828.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01661.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.41.8.922-b"},{"issue":"1","key":"e_1_2_6_8_2","first-page":"472a","article-title":"Clinically significant anti HI in two patients with greatly increased i antigen on their red cells [abstract]","volume":"90","author":"Arndt P","year":"1997","journal-title":"Blood"},{"key":"e_1_2_6_9_2","first-page":"101A","article-title":"Unusual IH\u2010like antibody implicated in delayed hemolytic transfusion reaction [abstract]","volume":"43","author":"Read SM","year":"2003","journal-title":"Transfusion"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1537-2995.2011.03209.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1537-2995.2011.03209.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T01:05:27Z","timestamp":1697245527000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1537-2995.2011.03209.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,9]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1111\/j.1537-2995.2011.03209.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1537-2995.2011.03209.x","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,9]]}}}