{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T17:13:07Z","timestamp":1774977187777,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,7,13]],"date-time":"2012-07-13T00:00:00Z","timestamp":1342137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Since 2007, large outbreaks of Q\u2003fever occurred in the Netherlands. The unprecedented number of Q\u2003fever infections resulted in the need for the Dutch blood transfusion service to evaluate the risk of transmission of <jats:italic>Coxiella burnetii<\/jats:italic> via blood.<\/jats:p><jats:p><jats:bold>STUDY DESIGN AND METHODS:<\/jats:bold> A lookback procedure (recipient tracing) was performed for transfused blood products of whole blood donors with confirmed <jats:italic>C.\u2003burnetii<\/jats:italic> infection within 3\u2003weeks before to 3\u2003weeks after blood donation. Repository samples of index donations were tested with real\u2010time polymerase chain reaction (PCR) for <jats:italic>C.\u2003burnetii<\/jats:italic> DNA. Hospitals were asked to review the medical records of recipients and\u2014if considered necessary\u2014to test the recipients for infection with <jats:italic>C.\u2003burnetii<\/jats:italic>.<\/jats:p><jats:p><jats:bold>RESULTS:<\/jats:bold> From 2007 through 2011, a total of 33 blood donors notified the blood bank of infection with <jats:italic>C.\u2003burnetii<\/jats:italic>. Thirteen donations fulfilled the criteria for a lookback procedure (18 blood products). <jats:italic>C.\u2003burnetii<\/jats:italic> PCR was positive in 1 of 13 repository samples of index donations. Blood products were transfused to 18 recipients. Information was retrieved from 12 of them; seven were tested for <jats:italic>C.\u2003burnetii<\/jats:italic>. Two recipients showed positive serology. However, transmission of <jats:italic>C.\u2003burnetii<\/jats:italic> via transfusion was unlikely, especially since most recipients lived in the same Q\u2003fever\u2013affected area as the donors.<\/jats:p><jats:p><jats:bold>CONCLUSION:<\/jats:bold> Blood donors who have clinical Q\u2003fever around the time of blood donation are unlikely to test positive for <jats:italic>C.\u2003burnetii<\/jats:italic> by PCR in repository samples. Transmission of <jats:italic>C.\u2003burnetii<\/jats:italic> via transfusion of blood products could not be demonstrated in a lookback exercise.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2012.03792.x","type":"journal-article","created":{"date-parts":[[2012,7,13]],"date-time":"2012-07-13T22:29:49Z","timestamp":1342218589000},"page":"716-721","source":"Crossref","is-referenced-by-count":13,"title":["Lookback procedures after postdonation notifications during a Q\u2003fever outbreak in the Netherlands"],"prefix":"10.1111","volume":"53","author":[{"given":"Marian G.J.","family":"van Kraaij","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed","family":"Slot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris M.","family":"Hogema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans L.","family":"Zaaijer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,7,13]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2003.09.001"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(05)70052-9"},{"key":"e_1_2_8_4_2","first-page":"1998","article-title":"An outbreak of Q\u2003fever in The Netherlands\u2014possible link to goats [in Dutch]","volume":"151","author":"Van Steenbergen JE","year":"2007","journal-title":"Ned Tijdschr Geneeskd"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268808001908"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268810002268"},{"key":"e_1_2_8_7_2","unstructured":"Anonymous.Q\u2010fever transmitted by blood transfusion\u2014United States. CDC public health notes1977."},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03250.x"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00454-09"},{"key":"e_1_2_8_10_2","unstructured":"National Institute for Public Health and the Environment (RIVM) the Netherlands.Q\u2010koorts [in Dutch].2012. [cited 2012 Jul 5]. Available from: URL:http:\/\/www.rivm.nl\/Onderwerpen\/Ziekten_Aandoeningen\/Q\/Q_koorts"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1973.tb110910.x"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5158.983"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.6.1087"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1086\/321878"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hci009"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcq113"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1537-2995.2012.03792.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1537-2995.2012.03792.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T16:40:32Z","timestamp":1697301632000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1537-2995.2012.03792.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,13]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/j.1537-2995.2012.03792.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1537-2995.2012.03792.x","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,13]]}}}