{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T15:27:33Z","timestamp":1778858853445,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":5977,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1111\/j.1538-7836.2006.02055.x","type":"journal-article","created":{"date-parts":[[2006,7,26]],"date-time":"2006-07-26T07:13:05Z","timestamp":1153897985000},"page":"1756-1762","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["DNA microarray analysis for the detection of mutations in hemophilia A"],"prefix":"10.1016","volume":"4","author":[{"given":"E.","family":"BERBER","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"LEGGO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"BROWN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"BERBER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"GALLO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"FEILOTTER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"LILLICRAP","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0010","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/312326a0","article-title":"Characterization of the human factor VIII gene","volume":"312","author":"Gitschier","year":"1984","journal-title":"Nature"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0015","unstructured":"HAMSTeRS. http:\/\/europium.csc.mrc.ac.uk (accessed 15 June 2006)."},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0020","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/nrg1617","article-title":"Haemophilia A: from mutation analysis to new therapies","volume":"6","author":"Graw","year":"2005","journal-title":"Nat Rev Genet"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0025","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1365-2516.2005.01069.x","article-title":"Mutation analysis in 51 patients with haemophilia A: report of 10 novel mutations and correlations between genotype and clinical phenotype","volume":"11","author":"Hill","year":"2005","journal-title":"Haemophilia"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0030","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1472-6483(10)60504-4","article-title":"Towards preimplantation diagnosis of cystic fibrosis using microarrays","volume":"8","author":"Salvado","year":"2003","journal-title":"Reprod Biomed Online"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0035","first-page":"457","article-title":"Ret oligonucleotide microarray for the detection of RET mutations in multiple endocrine neoplasia Type 2 syndromes","volume":"8","author":"Kim","year":"2002","journal-title":"Clin Cancer Res"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0040","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1101\/gr.8.12.1245","article-title":"Strategies for mutational analysis of the large multiexon ATM gene using high density oligonucleotide arrays","volume":"8","author":"Hacia","year":"1998","journal-title":"Genome Res"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0045","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/ng1296-441","article-title":"Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-color fluorescence analysis","volume":"14","author":"Hacia","year":"1996","journal-title":"Nat Genet"},{"issue":"Suppl. 1","key":"10.1111\/j.1538-7836.2006.02055.x_bb0050","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/4469","article-title":"Resequencing and mutational analysis using oligonucleotide microarrays","volume":"21","author":"Hacia","year":"1999","journal-title":"Nat Genet"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0055","doi-asserted-by":"crossref","first-page":"5444","DOI":"10.1093\/nar\/19.19.5444","article-title":"A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies","volume":"19","author":"Lahiri","year":"1991","journal-title":"Nucleic Acids Res"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0060","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1365-2516.2001.00453.x","article-title":"Determination of hemophilia A carrier status by mutation analysis","volume":"7","author":"Oranwiroon","year":"2001","journal-title":"Haemophilia"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0065","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s004390050636","article-title":"Factor VIII gene mutations found by a comparative study of SSCP, DGGE and CMC and their analysis on a molecular model of factor VIII protein","volume":"101","author":"Schwaab","year":"1997","journal-title":"Hum Genet"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0070","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/humu.10119","article-title":"High throughput mutation screening of the factor VIII gene (F8C) in hemophilia A: 37 novel mutations and Genotype-Phenotype correlation","volume":"20","author":"Citron","year":"2002","journal-title":"Hum Mutat"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0075","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0165-022X(00)00150-0","article-title":"Evaluation of DHPLC in the analysis of hemophilia A","volume":"47","author":"Oldenburg","year":"2001","journal-title":"J Biochem Biophys Methods"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0080","doi-asserted-by":"crossref","first-page":"5372","DOI":"10.1073\/pnas.0831102100","article-title":"Oligonucleotide microarrays demonstrate the highest frequency of ATM mutations in the mantle cell subtype of lymphoma","volume":"100","author":"Fang","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0085","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1146\/annurev.genom.1.1.329","article-title":"Sequence variation in genes and genomic DNA: methods for large-scale analysis","volume":"1","author":"Mir","year":"2000","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0090","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1101\/gr.2228504","article-title":"The human Mitochip: a high-throughput sequencing microarray for mitochondrial mutation detection","volume":"14","author":"Maitra","year":"2004","journal-title":"Genome Res"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0095","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1002\/ajh.20126","article-title":"Rapid detection of common Chinese Glucose-6-Phosphate Dehydrogenase (G6PD) Mutations by Microarray-Based Assay","volume":"76","author":"Bang-Ce","year":"2004","journal-title":"Am J Hematol"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0100","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/1098-1004(200010)16:4<354::AID-HUMU8>3.0.CO;2-V","article-title":"Oligonucleotide microarray based detection of repetitive sequence changes","volume":"16","author":"Hacia","year":"2000","journal-title":"Hum Mutat"},{"key":"10.1111\/j.1538-7836.2006.02055.x_bb0105","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1160\/TH05-02-0128","article-title":"Detection of known haemophilia B mutations and carrier testing by microarray","volume":"94","author":"Chan","year":"2005","journal-title":"Thromb Haemost"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1538-7836.2006.02055.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783622175501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783622175501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1538-7836.2006.02055.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:38:21Z","timestamp":1761532701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783622175501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S1538783622175501"],"URL":"https:\/\/doi.org\/10.1111\/j.1538-7836.2006.02055.x","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DNA microarray analysis for the detection of mutations in hemophilia A","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/j.1538-7836.2006.02055.x","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}