{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:08:56Z","timestamp":1761487736754},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T00:00:00Z","timestamp":1165536000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Risk Analysis"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>The potential consequences of the reintroduction of poliovirus in the post\u2010eradication era range from trivial (no or self\u2010limited transmission and no clinical cases) to very serious (return of continued transmission of polioviruses and abandonment of the poliomyelitis eradication goal). This paper summarises the key determinants of such outcomes and identifies factors relating to infection surveillance, to vaccination policies at the time of OPV cessation and beyond, and to the still\u2010unknown implications of these policies for infection transmission in environments with poor sanitation, as particularly important. Explicit consideration of these issues should encourage studies on the effectiveness of IPV vaccines in reducing poliovirus transmission in tropical environments, and should influence the location and containment requirements of facilities for vaccine production and storage, and for poliovirus\u2010related research, in the era after cessation of OPV.<\/jats:p>","DOI":"10.1111\/j.1539-6924.2006.00855.x","type":"journal-article","created":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T21:02:50Z","timestamp":1165611770000},"page":"1533-1540","source":"Crossref","is-referenced-by-count":17,"title":["Perspective: Determinants of the Severity of Poliovirus Outbreaks in the Post Eradication Era"],"prefix":"10.1111","volume":"26","author":[{"given":"P. E. M.","family":"Fine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ritchie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,8]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"Global Polio Eradication Initiative: Strategic plan 2004\u20132008","author":"WHO","year":"2003"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/323897"},{"key":"e_1_2_6_4_2","first-page":"221","article-title":"Lessons from Cuba: mass campaign administration of trivalent oral poliovirus vaccine and seroprevalence of poliovirus neutralizing antibodies","volume":"72","author":"LagoMas P.","year":"1994","journal-title":"Bull WHO"},{"issue":"6","key":"e_1_2_6_5_2","first-page":"1471","article-title":"Risks of paralytic disease due to wild or vaccine\u2010derived poliovirus after eradication","volume":"26","author":"Duintjer Tebbens R. J.","journal-title":"Risk Analysis"},{"key":"e_1_2_6_6_2","first-page":"129","article-title":"Stopping a polio outbreak in the post\u2010eradication era","volume":"105","author":"Fine P. E. M.","year":"2001","journal-title":"Developments in Biologicals Progress in polio eradication: vaccine strategies for the end game"},{"key":"e_1_2_6_7_2","first-page":"31","article-title":"The role of routine polio immunization in the post\u2010certification era","volume":"82","author":"Sutter R. W.","year":"2004","journal-title":"Bull WHO"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwi206"},{"key":"e_1_2_6_9_2","first-page":"47","article-title":"Polio control after certification: major issues outstanding","volume":"82","author":"Fine P. E. M.","year":"2004","journal-title":"Bull WHO"},{"key":"e_1_2_6_10_2","unstructured":"Fine P. E. M. &Carneiro I. A. M.(1998).Transmissibility and persistence of oral polio vaccine viruses: Implications for the global poliomyelitis eradication initiative. Unpublished document prepared for WHO Polio Programme. May 85pp."},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009924"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.58.030603.123625"},{"key":"e_1_2_6_13_2","first-page":"1053","article-title":"Poliovirus infections in four unvaccinated children \u2013 Minnesota, August\u2013October 2005","volume":"54","author":"Centers for Disease Control and Prevention","year":"2005","journal-title":"Morbidity and Mortality Weekly Report"},{"issue":"6","key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1111\/j.1539-6924.2006.00843.x","article-title":"Evaluation of response scenarios to potential polio outbreaks using mathematical models","volume":"26","author":"Thompson K. 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