{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:52:56Z","timestamp":1758401576453},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2004,12,10]],"date-time":"2004-12-10T00:00:00Z","timestamp":1102636800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p> <jats:italic>Withdrawal of parasympathetic tone has been reported after ablation in the posteroseptal right atrium and has been attributed to injury of vagal efferent fibers. The purpose of this study was to assess the time course and predictors of autonomic dysfunction after slow pathway ablation. In 30 patients with AV nodal reentrant tachycardia, time\u2010 and frequency\u2010domain measures of heart rate variability (HRV) were measured before, 30 minutes after, and 1 day after slow pathway ablation. There were significant reductions in mean RR interval (724 \u00b1 163 vs 836 \u00b1 164 ms, P &lt; 0.05), SD of RR intervals (29 \u00b1 17 vs 40 \u00b1 18 ms, P &lt; 0.05), root mean squared difference (15 \u00b1 8 vs 29 \u00b1 17 ms, P &lt; 0.05), and high frequency power (4.1 \u00b1 0.4 vs 4.5 \u00b1 0.6 log<jats:sub>10<\/jats:sub>ms<jats:sup>2<\/jats:sup>, P &lt; 0.05) 30 minutes after ablation. However, these parameters returned to baseline 1 day after ablation. Multivariate regression identified isoproterenol dose during the diagnostic study (P = 0.02) and radiofrequency duration (P = 0.02) as statistically significant predictors of heart rate change (R<jats:sup>2<\/jats:sup>= 0.45). These findings suggest that changes in autonomic tone after ablation in the posteroseptal right atrium are transitory and resolve within 1 day of the procedure. These short\u2010term changes may be related to procedural variables rather than direct injury to vagal efferent fibers.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1540-8159.2004.00697.x","type":"journal-article","created":{"date-parts":[[2004,12,10]],"date-time":"2004-12-10T15:22:37Z","timestamp":1102692157000},"page":"1638-1643","source":"Crossref","is-referenced-by-count":8,"title":["Time Course and Predictors of Autonomic Dysfunction After Ablation of the Slow Atrioventricular Nodal Pathway"],"prefix":"10.1111","volume":"27","author":[{"given":"STEVEN M.","family":"MARKOWITZ","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DAVID J.","family":"CHRISTINI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KENNETH 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