{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:15:10Z","timestamp":1763036110413},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T00:00:00Z","timestamp":1140393600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p> <jats:italic>\n            <jats:bold>Objectives:<\/jats:bold> To investigate the clinical outcome of right and left atrial radiofrequency ablation after the first 12 months in patients with drug\u2010refractory persistent atrial fibrillation (AF), and to identify predictors of long\u2010term success.<\/jats:italic> <\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Methods:<\/jats:bold> We analyzed the clinical outcome of 74 consecutive patients with a follow\u2010up &gt;12 months who underwent right and left atrial ablation for persistent AF. Patients who did not present symptomatic or asymptomatic atrial tachyarrhythmias (AT) lasting &gt;30 seconds after the first 3 months of follow\u2010up were defined responders to pulmonary veins ablation.<\/jats:italic> <\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Results:<\/jats:bold> After a mean follow\u2010up of 20.2 \u00b1 6.3 months (12\u201336), 52\/74 (70%) patients were deemed responders. AT relapsed within the first 12 months in 19\/74 (26%) patients (17 AF and 2 left atrial flutter). Among those patients who did not relapse within the first 12 months, only 3 patients (5%) presented AF after the first year of follow\u2010up. At the multivariate analysis presence of early AT relapse and history of AF &gt;7 years inversely correlated with a successful long\u2010term clinical outcome.<\/jats:italic> <\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Conclusion:<\/jats:bold> Right and left atrial ablation, alone or in association with antiarrhythmic drugs, prevented AT relapses in 70% of patients with drug\u2010refractory persistent AF also after the first 12 months. Presence of AT relapse within the first 3 months and history of AF &gt;7 years identified patients with a lower probability of successful long\u2010term clinical outcome.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1540-8159.2006.00309.x","type":"journal-article","created":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T10:19:56Z","timestamp":1140430796000},"page":"153-158","source":"Crossref","is-referenced-by-count":15,"title":["Long\u2010Term Outcome of Right and Left Atrial Radiofrequency Ablation in Patients with Persistent Atrial Fibrillation"],"prefix":"10.1111","volume":"29","author":[{"given":"EMANUELE","family":"BERTAGLIA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GIUSEPPE","family":"STABILE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GAETANO","family":"SENATORE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PIETRO","family":"TURCO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GIOVANNI","family":"DONNICI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANTONIO","family":"DE SIMONE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MASSIMO","family":"FAZZARI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FRANCESCA","family":"ZERBO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PIETRO","family":"PASCOTTO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00823.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1161\/hc4601.098517","article-title":"Atrial electroanatomical remodeling after circumferential radiofrequency pulmonary vein ablation: Efficacy of an anatomic approach in a large cohort of patients with atrial fibrillation","volume":"104","author":"Pappone C","year":"2001","journal-title":"Circulation"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.20.2463"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.03047.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00577-1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:JICE.0000026915.02503.92"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.00003.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2003.00033.x"},{"key":"e_1_2_6_11_2","first-page":"S139","article-title":"Predictive value of early atrial fibrillation recurrence after circumferential pulmonary vein ablation","volume":"1","author":"Bertaglia E","year":"2004","journal-title":"Heart Rhythm"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1998.tb00114.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03538.x"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8159.2006.00309.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8159.2006.00309.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T16:58:43Z","timestamp":1697129923000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8159.2006.00309.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["10.1111\/j.1540-8159.2006.00309.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8159.2006.00309.x","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}