{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T17:26:51Z","timestamp":1751822811997},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2007,4,29]],"date-time":"2007-04-29T00:00:00Z","timestamp":1177804800000},"content-version":"vor","delay-in-days":4258,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[1995,9]]},"abstract":"<jats:p>Influence of Slow Pathway Ablation on Atrial Fibrillation. <jats:italic>Introduction<\/jats:italic>: The mechanisms whereby radiofrequency catheter modification of AV nodal conduction slows the ventricular response are not well defined. Whether a successful modification procedure can be achieved by ablating posterior inputs to the AV node or by partial ablation of the compact AV node is unclear. We hypothesized that ablation of the well\u2010defined slow pathway in patients with AV nodal reentrant tachycardia would slow the ventricular response during atrial fibrillation.<\/jats:p><jats:p> <jats:italic>Methods and Results<\/jats:italic>: In 34 patients with dual AV physiology and inducible AV nodal reentrant tachycardia, atrial fibrillation was induced at baseline and immediately after successful slow pathway ablation and at 1\u2010week follow\u2010up. The minimal, maximal, and mean RR intervals during atrial fibrillation increased from 353 \u00b1 76,500 \u00b1 121, and 405 \u00b1 91 msec to 429 \u00b1 84 (P &lt; 0.01), 673 \u00b1 161 (P &lt; 0.01), and 535 \u00b1 98 msec (P &lt; 0.01), respectively. These effects remained stable during follow\u2010up at 1 week. The AV block cycle length increased from 343 \u00b1 68 msec to 375 \u00b1 60 msec (P &lt; 0.05) immediately and to 400 \u00b1 56 msec (P &lt; 0.01) at 1\u2010week follow\u2010up. The effective refractory period of the AV node prolonged from 282 \u00b1 83 msec to 312 \u00b1 89 msec and to 318 \u00b1 81 msec after 1 week (P &lt; 0.05), respectively.<\/jats:p><jats:p> <jats:italic>Conclusion<\/jats:italic>: This study shows a decrease in ventricular response to pacing\u2010induced atrial fibrillation after ablation of the slow pathway in patients with AV nodal reentrant tachycardia. Since the AV nodal conduction properties could be defined, this study supports the hypothesis that the main mechanism of AV nodal modification in chronic atrial fibrillation is caused by ablation of posterior inputs to the AV node.<\/jats:p>","DOI":"10.1111\/j.1540-8167.1995.tb00447.x","type":"journal-article","created":{"date-parts":[[2007,5,14]],"date-time":"2007-05-14T01:51:10Z","timestamp":1179107470000},"page":"711-715","source":"Crossref","is-referenced-by-count":12,"title":["Slowing of the Ventricular Rate During Atrial Fibrillation by Ablation of the Slow Pathway of AV Nodal Reentrant Tachycardia"],"prefix":"10.1111","volume":"6","author":[{"given":"J\u00dcRGEN","family":"TEBBENJOHANNS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DIETRICH","family":"PFEIFFER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BURGHARD","family":"SCHUMACHER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WERNER","family":"JUNG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MATTHIAS","family":"MANZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BERNDT","family":"L\u00dcDERITZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199410063311404"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.5.2299"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)00315-H"},{"key":"e_1_2_1_5_2","first-page":"1","article-title":"Ablation technique for ventricular rate control in atrial fibrillation: A no drug, no pacemaker option","volume":"90","author":"Roman CA","year":"1994","journal-title":"Circulation"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90759-5"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(94)90878-8"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199207303270504"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1993.tb01597.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.4.1086"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1993.tb01633.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.4.1318"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1993.tb01635.x"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(94)90471-5"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.1995.tb00447.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.1995.tb00447.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T04:12:14Z","timestamp":1698379934000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.1995.tb00447.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["10.1111\/j.1540-8167.1995.tb00447.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.1995.tb00447.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}