{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T04:03:35Z","timestamp":1758945815106},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"vor","delay-in-days":3761,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p>Implantable Defibrillators in Women. Clinical rhythm, heart disease, ejection fraction, defibrillation threshold, recurrent arrhythmias, and mortality were compared in 268 consecutive recipients (213 men and 55 women) of their first implantable cardioverter defibrillator for life\u2010threatening ventricular tachycardia or fibrillation. Women were younger than men, less likely to have structural heart disease, and more likely to have clinical ventricular fibrillation, a higher ejection fraction, and a lower defibrillation threshold. Complications of defibrillator placement were similar in both sexes. Unadjusted survival tended to be higher in women than in men (97% vs 90%, respectively, at 2 years, P = 0.08), largely due to fewer deaths from noncardiac causes or cardiac causes other than arrhythmia (P = 0.04). Women also tended to be at lower, albeit still substantial, risk for recurrent arrhythmias during follow\u2010up (37% vs 52% in men at 2 years, P = 0.11). After adjustment for baseline differences, overall survival, arrhythmia death\u2010free survival, nouarrhythmia death\u2010free survival, and frequency of recurrent arrhythmias were not found to be gender related. Despite their apparent \u201clower risk\u201d status on initial presentation, women remained at substantial risk for recurrent arrhythmias. This underscores the need to avoid being unduly biased by the \u201cappearance\u201d of health in managing women with malignant arrhythmias. That survival and other clinical endpoints were all ultimately independent of gender emphasizes the importance of other clinical variables in assessing risk from ventricular tachyarrhythmias.<\/jats:p>","DOI":"10.1111\/j.1540-8167.1997.tb00603.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T15:15:10Z","timestamp":1177082110000},"page":"2-10","source":"Crossref","is-referenced-by-count":20,"title":["Malignant Sustained Ventricular Tachyarrhythmias in Women:"],"prefix":"10.1111","volume":"8","author":[{"given":"PETER J.","family":"KUDENCHUK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GUST H.","family":"BARDY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JEANNE E.","family":"POOLE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"LEE DOLACK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARYE J.","family":"GLEVA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RAMU","family":"REDDY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GREGORY K.","family":"JONES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CHARLES","family":"TROUTMAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JILL","family":"ANDERSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GEORGE","family":"JOHNSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"208","volume-title":"Coronary Heart Disease in Women: Proceedings of an NIH Workshop","author":"Thom TJ","year":"1987"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1001\/archinte.1992.00400170062012","article-title":"Gender differences in the treatment and outcome of acute myocardial infarction. 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