{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:57:38Z","timestamp":1791046658755,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"vor","delay-in-days":3702,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[1997,3]]},"abstract":"<jats:p>RBBB, ST Elevation, and SCD. We recently described a syndrome characterized by an ECG pattern of right bundle branch block and persistent ST segment elevation in leads V<jats:sub>1<\/jats:sub> to V<jats:sub>3<\/jats:sub> in patients suffering from aborted sudden cardiac death and not having demonstrable structural heart disease. We present new observations on this syndrome, especially those related to asymptomatic and intermittent forms. Forty\u2010seven patients with the described ECG pattern were identified; 32 were symptomatic with syncope and sudden death aborted by cardiopulmonary resuscitation. Eleven patients received pharmacologic therapy, mainly amiodarone and\/or beta\u2010blocking agents, and 21 patients received an implantable defibrillator with or without pharmacologic therapy. Three of the 11 patients on pharmacologic therapy died suddenly during follow\u2010up, while 9 of 21 patients with an implantable defibrillator used the device during follow\u2010up. The remaining 15 patients were asymptomatic when first seen. Three patients died suddenly after 6 years, 3 months, and 2 months of follow\u2010up without treatment. Another patient received an implantable defibrillator after syncope and had subsequent episodes of ventricular fibrillation terminated by the defibrillator. The other 11 patients remain asymptomatic without (6) or with (5) treatment with beta blockers. In 14 of the 47 patients, the ECG normalized momentarily during follow\u2010up but later became abnormal again. During transient normalization of the ECG, administration of ajmaline or procainamide unmasked the described ECG pattern in six patients who received the drug. Long\u2010term follow\u2010up of survivors failed to show progression to any form of right or left ventricular cardiomyopatby.<\/jats:p>","DOI":"10.1111\/j.1540-8167.1997.tb00796.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T15:14:11Z","timestamp":1177082051000},"page":"325-331","source":"Crossref","is-referenced-by-count":187,"title":["Further Characterization of the Syndrome of Right Bundle Branch Block, ST Segment Elevation, and Sudden Cardiac Death"],"prefix":"10.1111","volume":"8","author":[{"given":"JOSEP","family":"BRUGADA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PEDRO","family":"BRUGADA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"746","article-title":"A distinct clinical and eleclrocardiographic syndrome: Right bundle branch block, persistent ST segment elevation with normal QT interval and sudden cardiac death","volume":"14","author":"Brugada P","year":"1991","journal-title":"PACE"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90253-J"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.68.6.1729"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.87.2.562"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1985.tb05908.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(94)90070-1"},{"key":"e_1_2_1_8_2","first-page":"525","article-title":"Changements electrocardiographiques observes chez un homme mort de froid","volume":"31","author":"Tomaszewski W","year":"1938","journal-title":"Arch Mal Coeur"},{"key":"e_1_2_1_9_2","first-page":"169","article-title":"The electro\u2010cardiographic features of hypothermia","volume":"7","author":"Solomon A","year":"1989","journal-title":"Am J Med"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.21.3.343"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.2.372"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.1997.tb00796.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.1997.tb00796.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T20:02:48Z","timestamp":1698436968000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.1997.tb00796.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,3]]}},"alternative-id":["10.1111\/j.1540-8167.1997.tb00796.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.1997.tb00796.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,3]]}}}