{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:33:18Z","timestamp":1762003998602},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"vor","delay-in-days":3276,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[1998,5]]},"abstract":"<jats:p><jats:bold>AVNRT and Sinus Node Dysfunction. <\/jats:bold><jats:bold> Introduction: <\/jats:bold> Sinus node dysfunction (SND) is frequently associated with impaired AV conduction. This study investigated the electrophysiologic properties of dual AV nodal pathways in patients suffering from both SND and AV nodal reentrant tachycardia (AVNRT).<\/jats:p><jats:p><jats:bold>Methods and Results: <\/jats:bold> Two groups of patients with slow\u2010fast AVNRT underwent invasive electrophysiologic testing and catheter ablation of the slow pathway. Group A comprised 10 patients with SND (age 70 \u00b1 8 years), (Group B included 10 age\u2010matched patients without SND (age 69 \u00b1 7 years; P = NS) who served as controls. Patients of group A exhibited prolongation of the anterograde Wenckebach cycle lengths (WBCLs) of both the fast pathway (559 \u00b1 96 vs 361 \u00b1 38 msec; P &lt; 0.01) and the slow pathway (409 \u00b1 57 vs 339 \u00b1 32 ms; P &lt; 0.01). However, the delta between the WBCLs of the fast and the slow pathways was larger in patients of group A (150 \u00b1 80 vs 22 \u00b1 20 msec; P &lt; 0.01). Retrograde fast pathway conduction was well preserved with no difference in WBCLs (356 \u00b1 42 vs 330 \u00b1 47 msec; P = NS). Cycle lengths of AVNRT were longer in group A (468 \u00b1 46 vs 363 \u00b1 37 msec; P &lt; 0.01). Clinically, all patients of group A suffered from multiple episodes of AVNRT per week, which was not the case in any patient of group B (P &lt; 0.01). Catheter ablation of the slow pathway eliminated AVNRT in all patients without complications.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> Patients with AVNRT and SND exhibit characteristic electrophysiologic alterations of both AV nodal pathways. Clinically, this results in significantly more frequent episodes of tachycardia. Slow pathway ablation appears to be safe and effective in these patients.<\/jats:p>","DOI":"10.1111\/j.1540-8167.1998.tb01838.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T14:43:44Z","timestamp":1177080224000},"page":"470-478","source":"Crossref","is-referenced-by-count":3,"title":["Atrioventricular Nodal Reentry Tachycardia in Patients with Sinus Node Dysfunction: Electrophysiologic Characteristics, Clinical Presentation, and Results of Slow Pathway Ablation"],"prefix":"10.1111","volume":"9","author":[{"given":"GERHARD","family":"KREINER","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BERNHARD","family":"FREY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HEINZ DAVID","family":"G\u00d6SSINGER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.44.6.1096"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1988.tb06287.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.46.1.5"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.37.6.583"},{"key":"e_1_2_1_6_2","first-page":"61","article-title":"Sick sinus syndrome: Current views","volume":"49","author":"Chung EK","year":"1980","journal-title":"Mod Concept Cardiovasc Dis"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1986.tb06678.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1979.tb03652.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90757-9"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.11.2023"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1996.tb00493.x"},{"key":"e_1_2_1_12_2","first-page":"1234","volume-title":"Cardiac Electrophysiology. 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