{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:26:47Z","timestamp":1759091207368},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"vor","delay-in-days":2850,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[1999,7]]},"abstract":"<jats:p><jats:bold>Noninvasive Diagnosis in Patients with Undocumented Tachycardias. <\/jats:bold>  <jats:italic>Introduction:<\/jats:italic> Patients with symptoms suggestive of paroxysmal supraventricular tachycardia (PSVT) but no tachycardia documentation often undergo diagnostic electrophysiologic study. In dual AV node physiology with AV node reentrant tachycardia (AVNRT), the anterograde fast pathway is more sensitive than the slow pathway to the effects of adenosine. The purpose of the study was to test the hypothesis that adenosine can be used as a bedside test for the diagnosis of dual AV node physiology and hence for AVNRT.<\/jats:p><jats:p> <jats:italic>Methods and Results:<\/jats:italic> During electrophysiologic study, 37 patients without prior documentation hut symptoms indicative for PSVT received incremental dosages of adenosine during sinus rhythm until second\u2010degree or greater AV block was observed. Suggestive signs of dual AV node physiology on the surface ECG (sudden jump of PQ interval \u2265 50 msec) were found in 13 (76%) of 17 patients with inducible AVNRT but in only 1 (5%) of the remaining patients (P &lt; 0.01). In the AVNRT group, the maximal increase of the PQ interval between two beats was greater (88 \u00b1 45 msec) than in the remaining 20 patients (17 \u00b1 11 msec) (P &lt; 0.01).<\/jats:p><jats:p> <jats:italic>Conclusion:<\/jats:italic> Careful evaluation of surface ECG during administration of adenosine helps to identify patients prone to AVNRT. The adenosine test is a valuable noninvasive adjunct in patients with undocumented palpitations suggestive of PSVT<\/jats:p>","DOI":"10.1111\/j.1540-8167.1999.tb01262.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T13:58:51Z","timestamp":1177077531000},"page":"916-923","source":"Crossref","is-referenced-by-count":12,"title":["Noninvasive Diagnosis in Patients with Undocumented Tachycardias:"],"prefix":"10.1111","volume":"10","author":[{"given":"J\u00dcRGEN","family":"TEBBENJOHANNS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL","family":"NIEHAUS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"THOMAS","family":"KORTE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HELMUT","family":"DREXLER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90334-5"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.77.4.795"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90185-4"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.1.47"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00386-0"},{"key":"e_1_2_1_7_2","first-page":"541","article-title":"Les effects de l'adenosine triphosphate (ATP) sur le noeud sinusal et le noeud auriculo\u2010ventriculaire chez l'homme. Variations selon le lieu d'injection","volume":"17","author":"Leclercq JF","year":"1978","journal-title":"Coeur Med Interne"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.3.549"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(97)80002-6"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1998.tb00121.x"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.59.4.427"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(89)90289-5"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1056\/NEJM199112053252306","article-title":"Adenosine and supraventricular tachycardia","volume":"5","author":"Camm AJ","year":"1991","journal-title":"N Engl J Med"},{"key":"e_1_2_1_14_2","first-page":"H734","article-title":"Isolated atrial myocytes: Adenosine and acetylcholine increase potassium conductance","volume":"244","author":"Belardinelli L.","year":"1983","journal-title":"Am J Physiol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/27.1.54"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009758501195"},{"key":"e_1_2_1_17_2","first-page":"319","article-title":"Adenosine\u2010induced changes in atrial action potential: Contribution of Ca and K currents","volume":"23","author":"Visentin S.","year":"1990","journal-title":"Am J Physiol"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.1999.tb01262.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.1999.tb01262.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T13:35:14Z","timestamp":1698500114000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.1999.tb01262.x"}},"subtitle":["Value of the Adenosine Test to Predict AV Nodal Reentrant Tachycardia"],"short-title":[],"issued":{"date-parts":[[1999,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1999,7]]}},"alternative-id":["10.1111\/j.1540-8167.1999.tb01262.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.1999.tb01262.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,7]]}}}