{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:17:03Z","timestamp":1763036223083},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"vor","delay-in-days":2545,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2000,5]]},"abstract":"<jats:p>Bimodal RR Interval Distribution, <jats:italic>Introduction:<\/jats:italic> Radiofrequency (RF) catheter modification of the AV node hi patients with atrial fibrillation (AF) is limited by an unpredictable decrease of the ventricular rate and a wish incidence of permanent AV block, A bimodal RR histogram has been suggested to serve as a predictor for successful outcome but the corresponding AV node properties have never been characterized, We hypothesized that a bimodal histogram indicates dual AV nodal physiology and predicts a better outcome after AV node modification in chronic AF.<\/jats:p><jats:p> <jats:italic>Methods and Results:<\/jats:italic> Thirty\u2010seven patients were prospectively subdivided into two groups according to the RR histogram of 24\u2010hour ECC monitoring, Before to RF ablation, internal cardioversion and programmed stimulation were performed, Among the 22 patients (group I) with a bimodal RR histogram, dual AV nodal physiology was found in 17 (779f) patients, Ablation significantly decreased ventricular rate with loss of the peak of short RR cycles after ablation (mean and maximal ventricular rates: 32% and 35% rate reduction, respectively; P &lt; 0,01), In 15 patients with a unimodal RR histogram (group II), dual AV nodal physiology was found in 2 (13%), and rate reductions were 16% and 17%, respectively, At 6 months, 3 (14%) patients in group 1 and 6 (40%) in group II underwent elective AV nodal ablation with pacemaker implantation due to intolerable rapid ventricular response to AF.<\/jats:p><jats:p> <jats:italic>Conclusion:<\/jats:italic> Bimodal RR interval distribution during chronic AF suggests the presence of dual AV nodal physiology and predicts a better outcome of RF ablation of the posterior atrionocdal input.<\/jats:p>","DOI":"10.1111\/j.1540-8167.2000.tb00001.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T13:25:56Z","timestamp":1177075556000},"page":"497-503","source":"Crossref","is-referenced-by-count":34,"title":["Bimodal RR Interval Distribution in Chronic Atrial Fibrillation:"],"prefix":"10.1111","volume":"11","author":[{"given":"J\u00dcRGEN","family":"TEBBENJOHANNS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BURGHARD","family":"SCHUMACHER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"THOMAS","family":"KORTE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL","family":"NIEHAUS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DIETRICH","family":"PFEIFFER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"113","article-title":"Long\u2010term follnw\u2010up after radiofrequency modification of the atrioventricular node in patients with atgrial fibrillation","volume":"27","author":"Morally F","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)00315-H"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199410063311404"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.5.2299"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1995.tb00772.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.41.5.783"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.9.2.305"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a062070"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.3.549"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.9.1690"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.11.2856"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.75.5.502"},{"key":"e_1_2_1_14_2","first-page":"H2333","article-title":"Evidence for functionally distinct dual atrial Inputs to the human AV node","volume":"267","author":"Stein KM","year":"1994","journal-title":"Am J Physiol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.2.277"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.4.1086"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1993.tb01635.x"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.80.4.951"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90788-6"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2000.tb00001.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2000.tb00001.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T08:08:28Z","timestamp":1698566908000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2000.tb00001.x"}},"subtitle":["Impact of Dual Atrioventricular Nodal Physiology on Long\u2010Term Rate Control after Catheter Ablation of the Posterior Atrionodal Input"],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,5]]}},"alternative-id":["10.1111\/j.1540-8167.2000.tb00001.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2000.tb00001.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}