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LQT3 patients may derive particular benefit from pacing because the dispersion of repolarization worsens steeply during bradycardia in this genotype. However, concluding that other genotypes will not benefit from pacing is premature. Pacing may he especially beneficial for patients with \u201cpause\u2010dependent\u201d arrhythmias. Programming should include a sufficiently fast lower rate limit. Features that allow heart rate slowing beyond the lower rate limit or that may trigger pauses <jats:italic>must<\/jats:italic> he programmed \u201coff\u201d because pauses are proarrhythmic in this population. Pause\u2010prevention pacing algorithms may he beneficial.<\/jats:p>","DOI":"10.1111\/j.1540-8167.2000.tb00015.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T13:25:56Z","timestamp":1177075556000},"page":"593-599","source":"Crossref","is-referenced-by-count":90,"title":["Cardiac Pacing in the Long QT Syndrome:"],"prefix":"10.1111","volume":"11","author":[{"given":"SAMI","family":"VISKIN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80203-6"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.84.4.1524"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90180-U"},{"key":"e_1_2_1_5_2","first-page":"I","article-title":"Long\u2010term follow\u2010up of patients with the idiopathic long QT syndrome treated with combined beta\u2010blockers and chronic pacing","volume":"96","author":"Dorostkar PC","year":"1997","journal-title":"Circulation"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)02107-8"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.140.8.1036"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(79)90326-6"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.6.2038"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.21.2314"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1161\/01.CIR.92.12.3381","article-title":"Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. 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