{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:28:05Z","timestamp":1790720885058,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T00:00:00Z","timestamp":1177027200000},"content-version":"vor","delay-in-days":2666,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>\n                    Trigger Ablation in Chronic AF.\n                    <jats:italic>Introduction<\/jats:italic>\n                    : We assessed the mode of reinitiation of atrial fibrillation (AF) after cardioversion and the efficacy of ablating these foci of reinitiation in patients with chronic AF.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods and Results<\/jats:italic>\n                    : Fifteen patients, 7 with structural heart disease, underwent mapping and catheter ablation of drug\u2010resistant AF documented to he persistent for 5 \u00b1 4 months. In all patients, cardioversion was followed by documentation of P on T atrial ectopy and early recurrence, which allowed mapping of the reinitiating trigger or the source of ectopy. Radiofrequency (RF) ablation was performed at pulmonary vein (PV) ostia using a target temperature of 50\u00b0C and a power limit of 30 to 40 W, with the endpoint being interruption of all local muscle conduction. A total of 32 arrhythmogenic PVs and 2 atrial foci (left septum and left appendage) were identified: 1, 2, and 3 or 4 PVs in 5, 3, and 6 patients. RF applications at the ostial perimeter resulted in progressively increasing delay, followed by abolition of PV potentials in 8, but potentials persisted in 6. A single ablation session was performed in 7 patients and 8 underwent two or three sessions because of recurrence of AF; ablation was directed at the same source due to recovery of local PV potential or at a different PV. No PV stenosis was noted either acutely or at repeated follow\u2010up angiograms. Nine patients (60%) were in stable sinus rhythm without antiarrhythmic drugs at follow\u2010up of 11 \u00b1 8 months. Anticoagulants were interrupted in 7 patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : PVs are the dominant triggers reinitiating chronic AF in this patient population. Elimination of PV potentials by ostial RF applications results in stable sinus rhythm in 60%. A larger group and longer follow\u2010up are needed to investigate further the role of trigger ablation in curative therapy for chronic AF.\n                  <\/jats:p>","DOI":"10.1111\/j.1540-8167.2000.tb00727.x","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T09:31:56Z","timestamp":1177061516000},"page":"2-10","source":"Crossref","is-referenced-by-count":158,"title":["Catheter Ablation of Chronic Atrial Fibrillation Targeting the Reinitiating Triggers"],"prefix":"10.1111","volume":"11","author":[{"given":"MICHEL","family":"HA\u00cfSSAGUERRE","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PIERRE","family":"JA\u00cfS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DIPEN C.","family":"SHAH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THOMAS","family":"ARENTZ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DIETRICH","family":"KALUSCHE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ATSUSHI","family":"TAKAHASHI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ST\u00c9PHANE","family":"GARRIGUE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00c9L\u00c8ZE","family":"HOCINI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JING TIAN","family":"PENG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JACQUES","family":"CL\u00c9MENTY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_1_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.6.1262"},{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1050"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.10.946"},{"key":"e_1_2_1_4_2","first-page":"548","volume-title":"Cardiac Electrophysiology: From Cell to Bedside","author":"Allessie MA","year":"1990"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)36723-6"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(93)90338-I"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(92)90312-R"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90293-3"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"II\u2010339","DOI":"10.1161\/01.CIR.92.9.359","article-title":"Modified Maze procedure for patients with atrial fibrillation undergoing simultaneous open heart surgery","volume":"92","author":"Kosakai Y","year":"1995","journal-title":"Circulation"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.8.2235"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.5.1588"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1996.tb00492.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.3.572"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.8.2715"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.12.1176"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.21.2136"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00956.x"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(93)91014-9"},{"key":"e_1_2_1_19_2","first-page":"803","article-title":"Single burn pulmonary vein isolation with a virtual circumferential electrode. (Abstract)","volume":"21","author":"Swartz J","year":"1998","journal-title":"PACE"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1998.tb01213.x"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.17.1769"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00714-6"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00691-3"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1999.tb00638.x"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1999.tb00240.x"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.34.3.412"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1051450403"},{"key":"e_1_2_1_28_2","first-page":"133","article-title":"Node\u2010like cells in the myocardial layerof the pulmonary vein of rats: An ultrastructural study","volume":"145","author":"Masani F","year":"1986","journal-title":"J Anat"},{"key":"e_1_2_1_29_2","first-page":"239","article-title":"Functional anatomy of the junction of the left atrium and the pulmonary veins","volume":"62","author":"Cavalcanti JS","year":"1994","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.2170\/jjphysiol.17.174"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(72)90533-4"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(72)90009-4"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1981.sp013718"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/294582a0"},{"key":"e_1_2_1_35_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.6.800"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.23.3028"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(91)90707-R"},{"key":"e_1_2_1_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1998.tb00157.x"},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1954"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.7.1600"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.3.562"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(96)00613-3"},{"key":"e_1_2_1_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(92)90075-F"},{"key":"e_1_2_1_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(97)00252-2"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2000.tb00727.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2000.tb00727.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T02:39:43Z","timestamp":1698547183000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2000.tb00727.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1111\/j.1540-8167.2000.tb00727.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2000.tb00727.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}