{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:31:52Z","timestamp":1789201912729,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:p> <jats:italic>Introduction:<\/jats:italic> Dual atrioventricular (AV) nodal physiology, defined as an AH jump \u226550 msec with a 10 msec decrease in A1A2, is the substrate for atrioventricular nodal reentrant tachycardia (AVNRT) and yet it is present in a minority of pediatric patients with AVNRT. Our objective was to characterize dual AV nodal physiology as it pertains to a pediatric population.<\/jats:p><jats:p> <jats:italic>Methods\/Results:<\/jats:italic> We retrospectively reviewed invasive electrophysiology studies in 92 patients with AVNRT (age12.1 \u00b1 3.7 yrs) and in 46 controls without AVNRT (age 13.3 \u00b1 3.7 yrs). Diagnoses in controls: syncope (N = 31), palpitations (N = 6), atrial flutter (N = 3), history of atrial tachycardia with no inducible arrhythmia (N = 3), and ventricular tachycardia (N = 3). General anesthesia was used in 49% of AVNRT and 52% of controls, P = 0.86. There were no differences in PR, AH, HV, or AV block cycle length. With A1A2 atrial stimulation, AVNRT patients had a significantly longer maximum AH achieved (324 \u00b1 104 msec vs 255 \u00b1 67 msec, P = 0.001), and a shorter AVNERP (276 \u00b1 49 msec vs 313 \u00b1 68 msec P = 0.0005). An AH jump \u226550 msec was found in 42% of AVNRT versus 30% of controls (P = 0.2). Using a ROC graph we found that an AH jump of any size is a poor predictor of AVNRT. With atrial overdrive pacing, PR \u2265 RR was seen more commonly in AVNRT versus controls, (55\/91(60%) vs 6\/46 (13%) P = 0.000).<\/jats:p><jats:p> <jats:italic>Conclusions:<\/jats:italic> Neither the common definition of dual AV nodes or redefining an AH jump as some value &lt;50 msec are reliable methods to define dual AV nodes or to predict AVNRT in pediatric patients. PR \u2265 RR is a relatively good predictor of AVNRT.<\/jats:p>","DOI":"10.1111\/j.1540-8167.2006.00452.x","type":"journal-article","created":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T10:05:50Z","timestamp":1141207550000},"page":"638-644","source":"Crossref","is-referenced-by-count":31,"title":["Characterizing Dual Atrioventricular Nodal Physiology in Pediatric Patients with Atrioventricular Nodal Reentrant Tachycardia"],"prefix":"10.1111","volume":"17","author":[{"given":"DOMINIC J.","family":"BLURTON","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNE M.","family":"DUBIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NANCY A.","family":"CHIESA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GEORGE F.","family":"VAN HARE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KATHRYN K.","family":"COLLINS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,3]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.1.282"},{"key":"e_1_2_6_3_2","first-page":"620","volume-title":"Cardiac Electrophysiology: From Cell to Bedside","author":"Jackman WM","year":"1995"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(96)90307-5"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.3.549"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.43.5.679"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1996.tb00529.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90858-V"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2000.tb00830.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2002.00203.x"},{"key":"e_1_2_6_11_2","first-page":"S50","article-title":"Utility of sustained slow pathway conduction to assess efficacy of catheter ablation of atrioventricular nodal reentry tachycardia in children","volume":"1","author":"Kannankeril PJ","year":"2004","journal-title":"Heart Rhythm"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2003.t01-1-00252.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2000.tb01761.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00487-1"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2006.00452.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2006.00452.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T20:08:02Z","timestamp":1696968482000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2006.00452.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1111\/j.1540-8167.2006.00452.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2006.00452.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3]]}}}