{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:30:51Z","timestamp":1761561051834},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2006,5,2]],"date-time":"2006-05-02T00:00:00Z","timestamp":1146528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:p> <jats:italic>Introduction:<\/jats:italic> The acceptance of atrial arrhythmia features in implantable cardioverter defibrillators (ICDs) will depend on their ability to appropriately discriminate atrial tachyarrhythmias\/atrial fibrillation (AT\/AF). This study tested the effectiveness of an atrial\/ventricular ICD with advanced atrial detection and new algorithms designed to prevent atrial arrhythmias.<\/jats:p><jats:p> <jats:italic>Methods and Results:<\/jats:italic> Ninety\u2010five patients were implanted with a dual chamber ICD (Model 1900, Guidant Corporation, MN, USA) at 25 US centers. Ten patients received a coronary sinus (CS) lead allowing a defibrillation vector for AT\/AF cardioversion. Follow\u2010up was 12.2 months. The addition of new atrial features designed for detection, discrimination, and prevention of AT\/AF had no adverse effect upon detection of induced ventricular fibrillation (VF) (mean detection time with new features ON was 2.22 seconds vs 2.19 seconds with features OFF). A total of 100% of the induced and spontaneous ventricular and atrial arrhythmias receiving shock therapy were reviewed as appropriate detection. Atrial shock conversion efficacy for spontaneous and induced AT\/AF episodes was 83% and 96%, respectively (144 spontaneous, 162 induced episodes). A 3\u2010month randomized crossover trial of atrial preventative pacing features did not result in adverse effects, but there was no clinical efficacy for prevention of AT\/AF.<\/jats:p><jats:p> <jats:italic>Conclusion:<\/jats:italic> Enhanced atrial detection and discrimination features combined with tiered atrial therapies did not adversely impact the ability of the ICD (Model 1900) to appropriately detect and treat ventricular tachyarrhythmias.<\/jats:p>","DOI":"10.1111\/j.1540-8167.2006.00498.x","type":"journal-article","created":{"date-parts":[[2006,5,3]],"date-time":"2006-05-03T05:58:33Z","timestamp":1146635913000},"page":"852-856","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Experience with Tiered Atrial Therapies and Atrial Arrhythmia Prevention Algorithms in a Dual Chamber Cardioverter Defibrillator"],"prefix":"10.1111","volume":"17","author":[{"given":"EMILE 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