{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:30:40Z","timestamp":1791477040615,"version":"4.3.4"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,1,8]],"date-time":"2007-01-08T00:00:00Z","timestamp":1168214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic>Introduction:<\/jats:italic>\n                      Ambulatory electrocardiographic monitoring systems are frequently used in the outpatient evaluation of symptoms suggestive of a cardiac arrhythmia; however, they have a low yield in the identification of clinically significant but infrequent, brief, and\/or intermittently symptomatic arrhythmias. The purpose of this study was to compare the relative value of a mobile cardiac outpatient telemetry system (MCOT) with a patient\u2010activated external looping event monitor (LOOP) for symptoms thought to be due to an arrhythmia.\n                    <\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Methods and Results:<\/jats:italic>\n                      The study was a 17\u2010center prospective clinical trial with patients randomized to either LOOP or MCOT for up to 30 days. Subjects with symptoms of syncope, presyncope, or severe palpitations who had a nondiagnostic 24\u2010hour Holter monitor were randomized. The primary endpoint was the confirmation or exclusion of a probable arrhythmic cause of their symptoms. A total of 266 patients who completed the monitoring period were analyzed. A diagnosis was made in 88% of MCOT subjects compared with 75% of LOOP subjects (P = 0.008). In a subgroup of patients presenting with syncope or presyncope, a diagnosis was made in 89% of MCOT subjects versus 69% of LOOP subjects (P = 0.008). MCOT was superior in confirming the diagnosis of clinical significant arrhythmias, detecting such events in 55 of 134 patients (41%) compared with 19 of 132 patients (15%) in the LOOP group (P &lt; 0.001).\n                    <\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Conclusions:<\/jats:italic>\n                      MCOT provided a significantly higher yield than standard cardiac loop recorders in patients with symptoms suggestive of a significant cardiac arrhythmia.\n                    <\/jats:bold>\n                  <\/jats:p>","DOI":"10.1111\/j.1540-8167.2006.00729.x","type":"journal-article","created":{"date-parts":[[2007,1,8]],"date-time":"2007-01-08T11:25:40Z","timestamp":1168255540000},"page":"241-247","source":"Crossref","is-referenced-by-count":169,"title":["The Diagnosis of Cardiac Arrhythmias: A Prospective Multi\u2010Center Randomized Study Comparing Mobile Cardiac Outpatient Telemetry Versus Standard Loop Event Monitoring"],"prefix":"10.1111","volume":"18","author":[{"given":"STEVEN A.","family":"ROTHMAN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JAMES C.","family":"LAUGHLIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JONATHAN","family":"SELTZER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JASJIT S.","family":"WALIA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RAKESH I.","family":"BAMAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SAMER Y.","family":"SIOUFFI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROBERT M.","family":"SANGRIGOLI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PETER R.","family":"KOWEY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,8]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1001\/archinte.1990.00390170103022","article-title":"The duration of Holter monitoring in patients with syncope. Is 24 hours enough?","volume":"150","author":"Bass EB","year":"1990","journal-title":"Arch Int Med"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90628-3"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2000.tb00400.x"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.08.003"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2003.t01-1-00277.x"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.12.015"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-1_Part_1-199601010-00003"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00233-X"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmi048"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2003.10.036"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.01.025"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960260405"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-128-11-199806010-00002"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2006.00729.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2006.00729.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T22:13:55Z","timestamp":1697062435000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2006.00729.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,8]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1111\/j.1540-8167.2006.00729.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2006.00729.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,8]]}}}