{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:32:48Z","timestamp":1761561168498},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T00:00:00Z","timestamp":1181952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:p> <jats:italic>Introduction:<\/jats:italic> Idiopathic left ventricular tachycardia (VT) originating from the left posterior fascicle can be eliminated by ablation at sites with abnormal diastolic potentials (DPs) during sinus rhythm. We investigated whether such DPs can also be recorded in patients with structural heart disease and VT involving the left bundle\u2010Purkinje system.<\/jats:p><jats:p> <jats:italic>Methods and Results:<\/jats:italic> Eight patients (mean age 67 \u00b1 11 years) with nonischemic cardiomyopathy (n = 5) or prior myocardial infarction (n = 3) presented with VT involving the left bundle\u2010Purkinje system (cycle length 376 \u00b1 45 ms). Three types of VT were observed: macroreentrant VT with participation of both left bundle fascicles in three patients, fascicular VT involving the left posterior fascicle in two patients, and scar\u2010related VT with Purkinje fibers as part of the reentrant circuit in three patients. In all patients, abnormal isolated DPs of low amplitude with a QRS\u2014earliest DP interval of 374 \u00b1 86 ms were found during sinus rhythm in the mid\u2010 or inferior left ventricular septum in areas with Purkinje potentials. The abnormal DPs during sinus rhythm coincided or were in proximity to DPs during the VT in six patients. VT ablation targeting the sites with the earliest abnormal DPs during sinus eliminated the VT in 7 of 8 patients with freedom from VT recurrence in six patients during the follow\u2010up of 11 \u00b1 5 months.<\/jats:p><jats:p> <jats:italic>Conclusions:<\/jats:italic> Isolated DPs during sinus rhythm were found in proximity to the posterior Purkinje network in patients with VT involving the left bundle\u2010Purkinje system associated with heart disease and can be used to guide successful catheter ablation.<\/jats:p>","DOI":"10.1111\/j.1540-8167.2007.00880.x","type":"journal-article","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T14:28:10Z","timestamp":1182004090000},"page":"808-817","source":"Crossref","is-referenced-by-count":10,"title":["Ventricular Tachycardia With Participation of the Left Bundle\u2010Purkinje System in Patients With Structural Heart Disease: Identification of Slow Conduction During Sinus 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