{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:02:07Z","timestamp":1787014927877,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,11,17]],"date-time":"2009-11-17T00:00:00Z","timestamp":1258416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic>Introduction:<\/jats:italic>\n                    <\/jats:bold>\n                    Recent expert consensus guidelines mention that one of the principles for infected device replacement following removal is to \u201creevaluate carefully if there is a continued need for a new cardiac device replacement.\u201d This is a Class I recommendation, which nevertheless suffers from a very low level of evidence (level of evidence C), since no study has revisited the systematic practice of reimplanting the same device based on a meticulous clinical reassessment. In the present paper, we examined the safety of withholding the implantation of pacing systems in selected patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Methods and Results:<\/jats:italic>\n                    <\/jats:bold>\n                    Between January 2005 and December 2007, 188 consecutive patients underwent extractions of infected pacing systems at 2 medical centers. \u201cLow\u2010risk\u201d patients were identified by (1) a spontaneous heart rate &gt;45 bpm, (2) no symptomatic asystole during monitoring, (3) QRS duration &lt;120 ms when history of AV block was noted, (4) no high\u2010degree AV block during continuous monitoring. They remained device\u2010free, unless an adverse clinical event occurred mandating the reimplantation. The primary study endpoint was rate of sudden death and syncope after a 12\u2010month follow\u2010up. Among the 74 (39.4%) \u201clow\u2010risk\u201d patients, a single patient suffered a bradycardia\u2010related syncopal event corresponding to a 1.3% (95% CI, 0.0\u20133.9) rate of primary endpoint. Pacing systems were also reimplanted in 24 patients (32.4%) for syncope (n = 1), nonsevere bradycardia\u2010reated symptoms (n = 17), cardiac resynchronization (n = 2), and for reassurance in 4 asymptomatic patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Conclusion:<\/jats:italic>\n                    <\/jats:bold>\n                    After removal of infected pacing systems, these preliminary data demonstrated that a strategy of nonsystematic device reimplantation associated with close surveillance was safe in \u201clow\u2010risk\u201d patients, allowing the administration of antimicrobials in a device\u2010free state.\n                    <jats:italic>(J Cardiovasc Electrophysiol, Vol. 21, pp. 540\u2010544, May 2010)<\/jats:italic>\n                  <\/jats:p>","DOI":"10.1111\/j.1540-8167.2009.01654.x","type":"journal-article","created":{"date-parts":[[2009,11,17]],"date-time":"2009-11-17T16:23:16Z","timestamp":1258474996000},"page":"540-544","source":"Crossref","is-referenced-by-count":7,"title":["Safety of Deferring the Reimplantation of Pacing Systems After Their Removal for Infectious Complications in Selected Patients: A 1\u2010Year Follow\u2010Up Study"],"prefix":"10.1111","volume":"21","author":[{"given":"ELOI","family":"MARIJON","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MAXIME","family":"DE 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