{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T22:20:15Z","timestamp":1784931615659,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2010,12,6]],"date-time":"2010-12-06T00:00:00Z","timestamp":1291593600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:p> <jats:bold>Intracardiac Echo Supported Cryoballoon Ablation<\/jats:bold>.\u2002<jats:bold><jats:italic>Introduction:<\/jats:italic><\/jats:bold> Cryoballoon ablation has been adopted for pulmonary vein (PV) isolation (PVI) in many centers. Complete occlusion of PV by an adequately sized balloon is crucial for effectiveness of cryoenergy delivery. The aim of this study was to evaluate intracardiac echocardiography (ICE) as an alternative imaging technique compared to angiographic imaging in cryoballoon PVI.<\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Methods and Results:<\/jats:italic>\n          <\/jats:bold> A total of 75 PVs were treated in 22 patients (61 \u00b1 13 years, 17 male) undergoing PV cryoballoon ablation for drug refractory paroxysmal atrial fibrillation. Decision for an adequate balloon size was based on diameters of the PV antra assessed by ICE and PV angiography. Per PV 2.4 \u00b1 0.4 cryoenergy pulses were applied. Decision for the balloon size was similar either based upon angiography or on ICE. A single 23 or 28 mm balloon was chosen in 10 and 3 patients, respectively. Two different sized balloons were used in 9 patients. PVI was evaluated after 2 cryoenergy applications. Total occlusion of the PV confirmed by ICE color flow Doppler (CFD) during ablation predicted successful PVI in 70 of 75 (93%) and unsuccessful PVI in 8 of 8 (100%). PV flow registered by pulsed wave Doppler at the PV ostium pre\u2010 and postablation was 0.48 \u00b1 0.10 and 0.51 \u00b1 0.12 m\/s, respectively (n.s.). PVI was finally confirmed by entrance block in all PVs. No procedural complications occurred.<\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Conclusions:<\/jats:italic>\n          <\/jats:bold> ICE is a feasible novel imaging technique in cryoballoon ablation procedures. It allows decision for adequate balloon size, exact balloon placement, prediction of acute ablation success, and excludes acute narrowing of PV ostia. <jats:italic>(J Cardiovasc Electrophysiol, Vol. 21, pp. 1325\u20101330, December 2010)<\/jats:italic><\/jats:p>","DOI":"10.1111\/j.1540-8167.2010.01813.x","type":"journal-article","created":{"date-parts":[[2010,6,9]],"date-time":"2010-06-09T22:01:27Z","timestamp":1276120887000},"page":"1325-1330","source":"Crossref","is-referenced-by-count":42,"title":["Cryoballoon Pulmonary Vein Isolation Supported by Intracardiac Echocardiography: Integration of a Nonfluoroscopic Imaging Technique in Atrial Fibrillation Ablation"],"prefix":"10.1111","volume":"21","author":[{"given":"GEORG","family":"N\u00d6LKER","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOHANNES","family":"HEINTZE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KLAUS\u2010J\u00dcRGEN","family":"GUTLEBEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BOGDAN","family":"MUNTEAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"VANESSA","family":"P\u00dcTZ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AMEERA","family":"YALDA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00dcRGEN","family":"VOGT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DIETER","family":"HORSTKOTTE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.177292"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.04.021"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn570"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm227"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00816.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01560.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01549.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1540-8167.2009.01668.x","article-title":"A novel cryoballoon technique for mapping and isolating pulmonary veins: A feasibility and efficacy study","volume":"21","author":"Tang M","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01600.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01524.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000070541.83326.15"},{"key":"e_1_2_6_13_2","article-title":"Die Pulmonalvenenisolation mit dem kleinen 23 mm Cryo\u2010Ballon bei paroxysmalem Vorhofflimmern ist hoch effektiv und kann zu einer PTCA \u00e4hnlichen Methode vereinfacht werden (Abstract)","volume":"98","author":"Keweloh B","year":"2009","journal-title":"Clin Res Cardiol"},{"key":"e_1_2_6_14_2","first-page":"S706","article-title":"Long term efficacy and side effects of antral isolation of pulmonary veins with cryoballoon technique in a large patient cohort with atrial fibrillation (Abstract)","volume":"120","author":"Vogt J","year":"2009","journal-title":"Circulation"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000146952.49223.11"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2002.01076.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun313"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.01064.x"}],"container-title":["Journal of Cardiovascular 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