{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:14:39Z","timestamp":1774264479758,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T00:00:00Z","timestamp":1317168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:p><jats:bold>Predict AF. <jats:italic>Objective:<\/jats:italic><\/jats:bold> Since predictors of recurrence of atrial fibrillation (AF) after ablation procedures are poorly defined, this prospective study was conducted to assess the value of left atrial (LA) deformation imaging with two\u2010dimensional speckle\u2010tracking (2D\u2010ST) to predict AF recurrences after successful ablation procedures.<\/jats:p><jats:p><jats:bold>\n            <jats:italic>Methods and results:<\/jats:italic>\n          <\/jats:bold> One hundred and three consecutive patients (age 58.1 \u00b1 16.6 years, 72.8% male) with AF (76 paroxysmal, 27 persistent) and 30 matched controls underwent transthoracic echocardiography and 2D\u2010ST\u2010LA\u2010deformation analysis with assessment of LA\u2010radial and LA\u2010longitudinal strain (Sr, Sl), and velocities derived from the apical 4\u2010 and 2\u2010chamber views (4CV, 2CV). AF recurrence was assessed during 6 months of follow\u2010up. For determination of AF\u2010related LA changes, AF patients were compared to controls and patients with AF recurrences after ablation procedures (n = 30, 29.1%) were compared with patients who maintained sinus rhythm (n = 73, 70.9%). Atrial deformation capabilities were significantly reduced (P\u2003 &lt; \u20030.0005) in patients with AF (4CVSl 17.8 \u00b1 13.5%; 4CVSr 22.3 \u00b1 14.9%; 4CV\u2010velocities 2.53 \u00b1 0.97 seconds) when compared with controls (4CVSl 31.3 \u00b1 12.4%; 4CVSr 30.3 \u00b1 9.1%; 4CV\u2010velocities 3.48 \u00b1 1.01 cm\/s). Independent predictors for AF recurrence after ablation procedures were 2CV\u2010LA\u2010global\u2010strain (Sr, P = 0.03; Sl, P = 0.003), 4CV\u2010LA\u2010gobal\u2010strain (Sr, P = 0.03; Sl, P = 0.02), and regional LA\u2010septal wall\u2010Sl (P = 0.008). LA\u2010global\u2010strain parameters were superior to regional LA function analysis for the prediction of AF recurrences, with cutoff values (cov), hazard ratios (HR), positive and negative predictive values (PPV, NPV) were: 4CVSl cov, 10.79% (HR 27.8, P\u2003 &lt; \u20030.0005; PPV 78.8%, NPV 93.9%), 4CVSr cov, \u221216.65% (HR 24.8, P &lt; 0.0005; PPV 69.4%, NPV 96.6%), 2CVSl cov, 12.31% (HR 22.7, P\u2003 &lt;\u2003 0.0005; PPV 75.8%, NPV 95.3%), and 2CVSr cov, \u221214.9% (HR 12.9, P &lt; 0.0005; PPV 64.3%, NPV 93.2%).<\/jats:p><jats:p><jats:bold>\n            <jats:italic>Conclusion:<\/jats:italic>\n          <\/jats:bold> Compared with controls, AF itself seems to decrease LA deformation capabilities. The assessment of global LA strain with 2D\u2010ST identifies patients with high risk for AF recurrence after ablation procedures. This imaging technique may help to improve therapeutic guiding for patients with AF. <jats:italic>(J Cardiovasc Electrophysiol, Vol. 23 p. 247\u2010255, March 2012.)<\/jats:italic><\/jats:p>","DOI":"10.1111\/j.1540-8167.2011.02177.x","type":"journal-article","created":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T16:45:07Z","timestamp":1317228307000},"page":"247-255","source":"Crossref","is-referenced-by-count":85,"title":["Left Atrial Deformation Imaging with Ultrasound Based Two\u2010Dimensional Speckle\u2010Tracking Predicts the Rate of Recurrence of Paroxysmal and Persistent Atrial Fibrillation After Successful Ablation Procedures"],"prefix":"10.1111","volume":"23","author":[{"given":"CHRISTOPH","family":"HAMMERSTINGL","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARIEKE","family":"SCHWEKENDIEK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DIANA","family":"MOMCILOVIC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROBERT","family":"SCHUELER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JAN\u2010MALTE","family":"SINNING","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JAN W.","family":"SCHRICKEL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ERICA","family":"MITTMANN\u2010BRAUN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GEORG","family":"NICKENIG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LARS","family":"LICKFETT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.04.005"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2000.tb00727.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.824789"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun018"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm027"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.9.3157"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.10.009"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1954"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000157153.30978.67"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859116"},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1161\/CIRCULATIONAHA.104.463125","article-title":"Atrial myocardial deformation properties predict maintenance of sinus rhythm after external cardioversion of recent\u2010onset lone atrial fibrillation: A color Doppler myocardial imaging and transthoracic and transesophageal echocardiographic study","volume":"112","author":"Di Salvo G","year":"2005","journal-title":"Circulation"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn227"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.12.005"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.109.865683"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-7-6"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.143.1.7063747"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn168"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.01.015"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.09.033"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2008.00707.x"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.811877"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2005.04407.x"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/sun030"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-0620(96)80039-9"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2011.02177.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2011.02177.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T01:32:51Z","timestamp":1698629571000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2011.02177.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,28]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1111\/j.1540-8167.2011.02177.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2011.02177.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,28]]}}}