{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T01:55:32Z","timestamp":1762998932229},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,27]],"date-time":"2012-03-27T00:00:00Z","timestamp":1332806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>Voltage\u2010Guided Cavotricuspid Isthmus Ablation.<\/jats:p><jats:p><jats:italic>Introduction:<\/jats:italic> The recently proposed \u201cmaximum voltage\u2010guided\u201d (MVG) technique for radiofrequency catheter ablation of atrial flutter targets high\u2010voltage electrograms along cavotricuspid isthmus (CTI) to ablate the functionally important anatomic muscle bundles alone, without drawing a complete anatomic line across the CTI. This innovative approach may shorten ablation time and procedure duration.<\/jats:p><jats:p><jats:bold>\n            <jats:italic>Methods and Results:<\/jats:italic>\n          <\/jats:bold> Within the multicenter AURUM 8 study, which compared 8\u2010mm gold\u2010 and Pt\u2010Ir\u2010tip catheters in atrial flutter ablation, we made a <jats:italic>post hoc<\/jats:italic> comparison of procedural data from 72 patients treated with MVG technique with data from 281 patients undergoing anatomic CTI ablation (unmatched) and with data from 72 patients selected from among those 281 patients such that they were matched with the MVG group with respect to selected baseline parameters and catheter type (matched). The MVG technique markedly reduced (P &lt; 0.001) ablation time (mean 6.9 minutes vs 10.9\/9.7 minutes [unmatched\/matched]), number of lesions (8.3 vs 13.7\/12.9), fluoroscopy time (9.5 minutes vs 20.6\/17.9 minutes), procedure duration (59 minutes vs 93\/86 minutes), and energy delivered (19 kJ vs 34\/30 kJ) compared with anatomic CTI ablation. The incidence of charring was higher for MVG than for anatomic ablation technique (31.9% vs 18.5\/15.3%, P &lt; 0.05), where Pt\u2010Ir tip catheters were 6\u2010fold more susceptible to charring than gold\u2010tip catheters (P &lt; 0.001), likely because of a lower thermal conductivity of the Pt\u2010Ir material. The acute success rate was slightly better for MVG than for anatomic ablation technique (97.2% vs 92.2\/91.7%, P = n.s.).<\/jats:p><jats:p><jats:bold>\n            <jats:italic>Conclusion:<\/jats:italic>\n          <\/jats:bold> Major procedural parameters are remarkably improved with MVG technique. Gold\u2010tip catheters are substantially less susceptible to charring and may therefore be preferred over Pt\u2010Ir\u2010tip catheters for MVG ablation technique.<\/jats:p><jats:p><jats:italic>(J Cardiovasc Electrophysiol, Vol. 23, pp. 479\u2010485, May 2012)<\/jats:italic><\/jats:p>","DOI":"10.1111\/j.1540-8167.2011.02252.x","type":"journal-article","created":{"date-parts":[[2012,3,29]],"date-time":"2012-03-29T13:22:25Z","timestamp":1333027345000},"page":"479-485","source":"Crossref","is-referenced-by-count":12,"title":["\u201cLargest Amplitude Ablation\u201d is the Optimal Approach for Typical Atrial Flutter Ablation: A Subanalysis from the AURUM 8 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