{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T23:15:35Z","timestamp":1770506135962,"version":"3.49.0"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,6,15]],"date-time":"2012-06-15T00:00:00Z","timestamp":1339718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p><jats:bold>Case Series of Mitral Isthmus Ablation.<\/jats:bold>\u2003<jats:italic>Background:<\/jats:italic> Mitral isthmus ablation is challenging. The use of steerable sheath and high ablation power may improve success rate.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> This single\u2010center, prospective study enrolled 200 patients who underwent ablation for atrial fibrillation (AF), including mitral isthmus ablation. Mitral isthmus ablation was performed using an irrigated ablation catheter via a steerable sheath (endocardium: maximum power: 40\/50 W limited to annular end, maximum temperature: 48 \u00b0C; coronary sinus [CS]: maximum power: 25\/30 W, maximum temperature: 48 \u00b0C). Endpoint was bidirectional mitral isthmus block.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Mitral isthmus block was acutely achieved in 182\/200 patients (91%). Sixty\u2010nine percent of patients required CS ablation. Mean total ablation time was 13 \u00b1 6 minutes. There was 1 case of acute circumflex artery occlusion. Mean left atrium (LA) diameter was significantly bigger in patients with unsuccessful mitral isthmus ablation (49 \u00b1 4 mm vs. 43 \u00b1 6 mm; P = 0.0007). In redo procedures, the incidence of reconduction at the mitral isthmus, roof and cavotricuspid isthmus was 44%, 37%, and 29%, respectively. Overall incidence of perimitral flutter was 9%. Prior complex fractionated atrial electrogram ablation was a predictor for microreentrant atrial tachycardia (AT) whereas gaps in linear lesions predicted macroreentrant flutters. After a mean follow\u2010up of 20 \u00b1 9 months, 73% of patients remained free from AF or AT.<\/jats:p><jats:p><jats:italic>Conclusion:<\/jats:italic> We reported on a series of mitral isthmus ablation using steerable sheath and high ablation power (50 W). Larger LA diameter was a predictor of failure to achieve mitral isthmus block. The mitral isthmus had a moderately high incidence of re\u2010conduction but was only associated with a relatively low incidence of perimitral flutter. <jats:italic>(J Cardiovasc Electrophysiol, Vol. 23, pp. 1193\u20131200, November 2012)<\/jats:italic><\/jats:p>","DOI":"10.1111\/j.1540-8167.2012.02380.x","type":"journal-article","created":{"date-parts":[[2012,5,20]],"date-time":"2012-05-20T15:07:01Z","timestamp":1337526421000},"page":"1193-1200","source":"Crossref","is-referenced-by-count":19,"title":["Mitral Isthmus Ablation Using Steerable Sheath and High Ablation Power: A Single Center Experience"],"prefix":"10.1111","volume":"23","author":[{"given":"KELVIN C. K.","family":"WONG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NORMAN","family":"QURESHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL","family":"JONES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KIM","family":"RAJAPPAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YAVER","family":"BASHIR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TIMOTHY R.","family":"BETTS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2005.00308.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2005.50192.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl093"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.774885"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.09.067"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn302"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02625.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.110.957761"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup069"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup434"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02112.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.01.042"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur019"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.561183"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01638.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.25.2928"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eum120"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.803650"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.04.030"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup151"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.924878"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.4.534"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01474-6"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000091081.19465.F1"},{"key":"e_1_2_6_26_2","volume-title":"Cardiac Electrophysiology: From Cell to Bedside","author":"Haines DE","year":"1995"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2006.00585.x"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03651.x"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03651.x"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2006.00645.x"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.964478"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.6.647"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup447"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2005.04.016"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.964817"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2012.02380.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2012.02380.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T20:25:08Z","timestamp":1698697508000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2012.02380.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,15]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1111\/j.1540-8167.2012.02380.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2012.02380.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,15]]}}}