{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:52:56Z","timestamp":1780541576435,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T00:00:00Z","timestamp":1347321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p><jats:bold>Clinical Outcome After Endoscopic PVI.<\/jats:bold>\u2002<jats:italic>Introduction:<\/jats:italic> The acute and long\u2010term outcome of pulmonary vein isolation (PVI) using an endoscopic ablation system (EAS) has only been reported in single\u2010center studies. The current prospective, multicenter study assessed the acute and 1\u2010year outcome following PVI using the EAS.<\/jats:p><jats:p><jats:italic>Methods and Results:<\/jats:italic> Seventy\u2010two patients (34 female, mean age 58 \u00b1 10 years) with a history (5 \u00b1 6 years) of drug\u2010refractory paroxysmal atrial fibrillation (AF) were included. Endoscopic PVI was performed in all patients. Follow\u2010up was based on regular telephone interviews, Holter ECG, and transtelephonic ECG recordings. Recurrence was defined as a symptomatic and\/or documented AF episode &gt;30 seconds following a blanking period of 3 months. In 72 patients, a total of 281 pulmonary veins (PVs) were targeted and 277\/281 (98.6%) PVs were isolated successfully using only the EAS. PV stenosis, thrombembolic events, pericardial effusion, pericardial tamponade, and phrenic nerve palsy occurred in 0 of 72, 0 of 72, 3 of 72 (4.2%), 4 of 72 (5.6%), and in 1 of 72 (1.4%) patients, respectively. Sixty\u2010seven of 72 (93.1%) patients completed a follow\u2010up of 365 days and 42 of 67 (62.7%) patients remained in stable sinus rhythm after a single procedure. A total of 13 of 25 (52%) patients suffering from AF recurrence consented to repeat PVI using conventional radiofrequency energy 221 \u00b1 121 days after the index procedure. LA to PV reconduction was found in 30 of 45 (67%) previously isolated PVs.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> A very high rate of acute electrical PVI is achieved using exclusively the EAS. The 1\u2010year single\u2010procedure success rate in patients with paroxysmal AF is comparable to conventional PVI. PV reconduction is the major determinant for AF recurrence.\u2002<jats:italic>(J Cardiovasc Electrophysiol, Vol. 24, pp. 7\u201013, January 2013)<\/jats:italic><\/jats:p>","DOI":"10.1111\/j.1540-8167.2012.02427.x","type":"journal-article","created":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T01:25:37Z","timestamp":1343784337000},"page":"7-13","source":"Crossref","is-referenced-by-count":34,"title":["Acute and Long\u2010Term Clinical Outcome After Endoscopic Pulmonary Vein Isolation: Results from the First Prospective, Multicenter Study"],"prefix":"10.1111","volume":"24","author":[{"given":"ANDREAS","family":"METZNER","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ERIK","family":"WISSNER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BORIS","family":"SCHMIDT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JULIAN","family":"CHUN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GERHARD","family":"HINDRICKS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHRISTOPHER","family":"PIORKOWSKI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FEIFAN","family":"OUYANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KARL\u2010HEINZ","family":"KUCK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm358"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.12.016"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000144459.37455.EE"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.690578"},{"key":"e_1_2_6_6_2","first-page":"269","article-title":"Longterm clinical results of 2 different ablation strategies in patients with paroxysmal and persistent atrial fibrillation","volume":"2008","author":"Gaita F","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.772582"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc0902.104712"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01101.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151289.73085.36"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.933283"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.840587"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.110.954149"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.01.022"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.01.022"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur356"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02247.x"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn570"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-006-8519-5"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm227"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00816.x"},{"key":"e_1_2_6_22_2","first-page":"126","article-title":"Pulmonary vein isolation by high intensity focused ultrasound","volume":"7","author":"Schmidt B","year":"2007","journal-title":"Indian Pacing Electrophysiol J"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.01.017"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.922930"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.01.019"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.03.059"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859116"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8167.2012.02427.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8167.2012.02427.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T16:56:05Z","timestamp":1697388965000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8167.2012.02427.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,11]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/j.1540-8167.2012.02427.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8167.2012.02427.x","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,11]]}}}