{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:05:23Z","timestamp":1760249123525},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,9]],"date-time":"2006-01-09T00:00:00Z","timestamp":1136764800000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:p> <jats:italic>Transthoracic echocardiography is a useful tool in the evaluation of patients with intrapulmonary and intracardiac shunts. We describe a case of a 49\u2010year\u2010old female with severe hypoxemia in the setting of aortic stenosis and cirrhosis of the liver. The use of agitated saline contrast during an echocardiography study helped to establish the diagnosis of intrapulmonary arteriovenous shunting consistent with the hepatopulmonary syndrome, thereby confirming the etiology of her symptoms and laboratory findings. This case report highlights the utility of echocardiography in diagnosing intrapulmonary shunts and assists in the understanding of the pathophysiology of hypoxemia in such patients.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1540-8175.2006.00131.x","type":"journal-article","created":{"date-parts":[[2006,1,9]],"date-time":"2006-01-09T12:41:43Z","timestamp":1136810503000},"page":"56-59","source":"Crossref","is-referenced-by-count":9,"title":["Echocardiographic Detection of Intrapulmonary Shunting in a Patient with Hepatopulmonary Syndrome: Case Report and Review of the Literature"],"prefix":"10.1111","volume":"23","author":[{"given":"Richard","family":"Pacca","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasad","family":"Maddukuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natesa G.","family":"Pandian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey T.","family":"Kuvin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,9]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.105.5.1528"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196602102740601"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v113.pm9247483"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.2.515"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1007369"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)61253-1"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13807-X"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(14)80166-1"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.1998.tb00584.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02164-0"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(98)70481-0"},{"key":"e_1_2_5_13_2","first-page":"1085","article-title":"Gas exchange and pulmonary vascular reactivity in patients with liver cirrhosis","volume":"135","author":"Rodriguez\u2010Roisin R","year":"1987","journal-title":"Am Rev Respir Dis"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8175.2006.00131.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8175.2006.00131.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T22:13:35Z","timestamp":1696976015000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8175.2006.00131.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1111\/j.1540-8175.2006.00131.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8175.2006.00131.x","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}