{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:36:06Z","timestamp":1789472166900,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,6,28]],"date-time":"2006-06-28T00:00:00Z","timestamp":1151452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:p> <jats:italic>Background: Left atrial appendage (LAA) dysfunction is an independent predictor of thromboembolism in mitral stenosis (MS). Objectives: To investigate whether there is a relation between annular velocities obtained by tissue Doppler imaging and LAA function and to determine if the annular velocities can predict the presence of the inactive LAA in MS. Methods: Eighty\u2010five MS patients and 80 healthy controls were evaluated by transthoracic echocardiography and all patients underwent transesophageal echocardiography. The annular systolic (S\u2010wave) and diastolic (E\u2010 and A\u2010waves) velocities were recorded. Inactive LAA was defined as LAA emptying velocity &lt;25 cm\/sec. Patients were divided into three groups; group I (n = 43): sinus rhythm (SR) and LAA emptying velocity \u226525 cm\/sec, group II (n = 15): SR and LAA emptying velocity &lt;25cm\/sec and group III (n = 27): atrial fibrillation. Results: Thrombus was detected in 12 patients and spontaneous echo contrast (SEC) was detected in 48 patients. Both S\u2010wave and peak LAA emptying velocities were decreasing, while SEC frequency and density were increasing from group I to group III. There was a positive correlation between LAA emptying and S\u2010wave velocities (P &lt; 0.001, r = 0.682). Multivariate regression analysis showed that only S\u2010wave is the independent predictor of inactive LAA (P = 0.001, odds ratio = 0.143, 95% CI = 0.047\u20130.434). In patients with SR, the cutoff value of S\u2010wave was 13.5 cm\/sec for the prediction of the presence of inactive LAA (sensitivity: 95.3%, specificity: 93.3%). Conclusions: S\u2010wave is an independent predictor of inactive LAA and a useful parameter in estimating inactive LAA in MS with SR.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1540-8175.2006.00260.x","type":"journal-article","created":{"date-parts":[[2006,6,28]],"date-time":"2006-06-28T10:47:48Z","timestamp":1151491668000},"page":"546-552","source":"Crossref","is-referenced-by-count":10,"title":["Mitral Annular Systolic Velocity Reflects the Left Atrial Appendage Function in Mitral Stenosis"],"prefix":"10.1111","volume":"23","author":[{"given":"Murat","family":"\u00c7ayl\u00fd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Kanada\u015fi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mesut","family":"Demir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esmeray","family":"Acart\u00fcrk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,6,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.82.5.547"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0742-2822.2004.03002.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(98)00128-4"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.1.99"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8175.2003.00004.x"},{"issue":"4","key":"e_1_2_6_7_2","first-page":"293","article-title":"Relationship of left atrial appendage function to left ventricular function","volume":"56","author":"Mahilmaran A","year":"2004","journal-title":"Indian Heart J"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0742-2822.2004.03064.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8175.2003.03022.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.04.025"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(89)80014-8"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(00)00235-7"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90644-0"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.2.485"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.2004.00550.x"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1042\/CS20010196"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.81.2.111"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.6.2356"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2002.116826"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(96)90478-2"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90878-8"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2000.103959"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0742-2822.2005.03131.x"},{"issue":"11","key":"e_1_2_6_24_2","first-page":"797","article-title":"Usefulness of multiplane transesophageal echocardiography in the recognition of artifacts and normal anatomical variants that may mimic left atrial thrombi in patients with atrial fibrillation","volume":"4","author":"Maltagliati A","year":"2003","journal-title":"Ital Heart J"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00472-6"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.024315"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1053\/euje.2001.0110"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(92)90978-5"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.28.10.973"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00454-9"},{"issue":"16","key":"e_1_2_6_31_2","first-page":"1252","article-title":"Working Group on Valvular Heart Disease. 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