{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T10:16:37Z","timestamp":1696760197464},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,11,2]],"date-time":"2011-11-02T00:00:00Z","timestamp":1320192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>Purpose: Right ventricular (RV) function plays an important role in the development of clinical symptoms, exercise capacity, prognosis, and survival in patients with mitral stenosis (MS). The purpose of this study was to evaluate global and regional RV systolic functions using a novel technique, VVI, in mild\u2010to\u2010moderate MS patients without clinical symptoms of heart failure. Methods: The study population consisted of 60 patients (mean age 51.7 \u00b1 11.6 years; 85% female) with isolated rheumatic mitral valve stenosis and 40 age\u2010 and sex\u2010matched control subjects (mean age 49.1 \u00b1 10.5 years; 76.7% female). Conventional echocardiography, tissue Doppler imaging (TDI), strain (S), and strain rate (SRs) analysis were performed in all patients. Results: Transmitral mean pressure gradient was 6.1 \u00b1 3.0 mmHg and mean mitral valve area was 1.41 \u00b1 0.31 cm<jats:sup>2<\/jats:sup> in patients with MS. TDI systolic velocity was significantly lower in MS patients compared to control subjects (0.13 \u00b1 0.03 m\/sec vs. 0.17 \u00b1 0.03 m\/sec; P &lt; 0.0001). RV\u2010isovolumic acceleration was reduced in MS patients (3.75 \u00b1 1.09 m\/sec<jats:sup>2<\/jats:sup> vs. 4.62 \u00b1 1.0 m\/sec<jats:sup>2<\/jats:sup>; P = 0.006). RV\u2010myocardial performance index was significantly increased in patients with MS (0.75 \u00b1 0.05 in MS and 0.29 \u00b1 0.04 in controls; P &lt; 0.0001) revealing impaired RV systolic and diastolic function. The mean longitudinal peak systolic S and SR were significantly reduced in patients with MS (P &lt; 0.0001). Conclusion: Our data revealed that RV systolic performance is reduced in patients with mild\u2010to\u2010moderate MS. 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