{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T09:41:19Z","timestamp":1698831679128},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,2,20]],"date-time":"2012-02-20T00:00:00Z","timestamp":1329696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>Background: Tissue synchronization imaging (TSI), a parametric imaging technique based on tissue velocity imaging, often demonstrates patterns other than lateral delay in patients evaluated for cardiac resynchronization therapy (CRT). The prevalence of these patterns and their response to CRT has not been well described. We hypothesized that regional patterns of dyssynchrony might correlate with the extent of reverse remodeling. Methods: A consecutive series of 32 patients underwent echocardiographic study prior to CRT implant and 3 months postimplant. TSI was used to color\u2010code the time\u2010to\u2010peak positive systolic velocity at six basal and six mid\u2010LV segments. Each patient was assigned to one of four groups based on the predominant location of greatest delay (\u22652 segments): (1) posterolateral delay, (2) septal delay, (3) no dyssynchrony, or (4) other. Results: Patients were classified as follows: posterolateral delay in 44% of patients (n = 14), septal delay in 28% (n = 9), no dyssynchrony in 16% (n = 5), and other pattern in 13% (n = 4). At 3\u2010month follow\u2010up, the group with the lateral delay pattern was associated with the greatest decrease in left ventricular end\u2010systolic volume (LVESV) and the largest improvement in left ventricular ejection fraction (LVEF) (\u221245 mL and +9.3%, respectively, P &lt; 0.05). The LVESV in the other three groups changed as follows: \u221224 mL (septal), \u221228 mL (no dyssynchrony), and \u221215 mL (other). Similar trends were observed for LVEF and left ventricular end\u2010diastolic volume. Conclusions: Despite the presence of wide QRS and a left bundle branch block, the most delayed segment is not always the posterolateral wall. Posterolateral delay is associated with the best response to CRT, while other patterns respond at a lower magnitude. (Echocardiography 2012;29:554\u2010559)<\/jats:p>","DOI":"10.1111\/j.1540-8175.2011.01656.x","type":"journal-article","created":{"date-parts":[[2012,2,20]],"date-time":"2012-02-20T17:09:23Z","timestamp":1329757763000},"page":"554-559","source":"Crossref","is-referenced-by-count":3,"title":["Regional Patterns of Dyssynchrony: Lateral Wall Delay Is Desirable but Not Essential for Left Ventricular Remodeling in Biventricular Pacing"],"prefix":"10.1111","volume":"29","author":[{"given":"John E.","family":"O'Mara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethan M.","family":"Fruechte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert T.","family":"Palac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore P.","family":"Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,2,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032423"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013168"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050496"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2006.05.001"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2006.02.001"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02938362"},{"issue":"2","key":"e_1_2_6_8_2","first-page":"S3","article-title":"Ventricular resynchronization: Pathophysiology and identification of responders","volume":"4","author":"Kass D","year":"2003","journal-title":"Rev Cardiovasc Med"},{"key":"e_1_2_6_9_2","first-page":"245","article-title":"Arrhythmias in patients with mechanical ventricular dysfunction and myocardial stretch: Role of mechano\u2010electric feedback","volume":"14","author":"Sarubbi B","year":"1998","journal-title":"Can J Cardiol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.23.2993"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.019"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00709-5"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc0402.102623"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.01.054"},{"key":"e_1_2_6_15_2","first-page":"88","volume-title":"The Echo Manual, 3rd Ed","author":"Oh J","year":"2006"},{"issue":"3","key":"e_1_2_6_16_2","first-page":"iii80\u2013iii87","article-title":"The role of tissue Doppler and strain imaging in predicting response to CRT","volume":"10","author":"Gorcsan J","year":"2008","journal-title":"Europace"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.09.027"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.508457"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.743120"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.07.011"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03604.x"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.09.058"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2005.11.014"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.06.043"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8175.2011.01656.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8175.2011.01656.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T11:42:26Z","timestamp":1698752546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8175.2011.01656.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,20]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["10.1111\/j.1540-8175.2011.01656.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8175.2011.01656.x","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,20]]}}}