{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T08:47:55Z","timestamp":1776588475592,"version":"3.51.2"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T00:00:00Z","timestamp":1338854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:p>Background: Heart failure is prevalent in end\u2010stage renal disease (ESRD) patients on long\u2010term dialysis. Detection of right ventricular (RV) dysfunction before starting dialysis may help to identify patients at a higher risk of developing heart failure. Aim: To assess RV function in predialysis patients using tissue Doppler imaging (TDI) derived myocardial performance index of RV (MPI\u2010RV). Methods: Echocardiography including pulsed TDI of lateral tricuspid annulus was performed in 41 patients with ESRD before starting dialysis therapy and 12 age and gender matched healthy controls. RV dysfunction was defined as MPI &gt; 0.4; a value above the median MPI in controls. Results: Compared to controls, ESRD patients had significantly higher blood pressure and lower hemoglobin level. MPI\u2010RV was significantly impaired in ESRD patients compared to control (0.6 vs. 0.4, P &lt; 0.001). RV dysfunction was identified in 23 ESRD patients (56%). ESRD patients had significantly lower e\u2019 velocity and e\u2019\/a\u2019 ratio as compared with controls. Pulmonary hypertension was detected in 15 (36.5%) patients. Among ESRD patients, no correlation was detected between MPI\u2010RV and calculated mean pulmonary artery pressure (r =\u20130.13, P = 0.47), pulmonary artery systolic pressure (r =\u20130.12, P = 0.6), left ventricular ejection fraction (r = 0.294, P = 0.06), or MPI of left ventricle (r = 0.3, P = 0.065). ESRD patients with and without pulmonary hypertension had similar MPI\u2010RV (0.6 vs.0.62, P = 0.32). Conclusion: Subclinical RV dysfunction\u2014as estimated by TDI derived MPI\u2014is highly prevalent among ESRD patients even before starting dialysis therapy. Pulmonary hypertension is not significantly associated with RV dysfunction in these patients.<\/jats:p>","DOI":"10.1111\/j.1540-8175.2012.01749.x","type":"journal-article","created":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T16:16:23Z","timestamp":1338912983000},"page":"1054-1059","source":"Crossref","is-referenced-by-count":22,"title":["Ventricular Function in Patients with End\u2010Stage Renal Disease Starting Dialysis Therapy: A Tissue Doppler Imaging 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