{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:54:17Z","timestamp":1777949657301,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T00:00:00Z","timestamp":1338854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:p>Aims: The aim of this study is to investigate the effect of mitral stenosis (MS) on left atrial (LA) function using two\u2010dimensional speckle tracking echocardiography (2DSTE). Methods and Results: The study subjects consisted of 52 patients with asymptomatic MS and 52 control subjects. LA function was assessed using prototype speckle tracking software and manual tracking method. Maximal LA volume (LAVmax) and minimal LA volume (LAVmin) and LA volume before atrial contraction (LAVpre\u2010a) were measured. Using these volumes, LA reservoir, conduit and booster pump fuction parameters were calculated. Indexed LAVmax, LAVmin, and LAVpre\u2010a measurements via speckle tracking were highly correlated with manual tracing methods in both groups. Expansion index (67.8 \u00b1 36.4 vs. 148.3 \u00b1 44.2), diastolic emptying index (37.7 \u00b1 12.9 vs. 58.0 \u00b1 8.5), passive emptying (37.3 \u00b1 14.1 vs. 70.4 \u00b1 10.4) and passive emptying index (13.3 \u00b1 6.3 vs. 41.3 \u00b1 10.6) were decreased significantly in MS patients (P &lt; 0.001). In contrast active emptying index (62.6 \u00b1 4.1 vs. 29.5 \u00b1 10.1) increased in MS group (P &lt; 0.001) while active emptying (28.1 \u00b1 13.0 vs. 28.3 \u00b1 6.9) remained same among both groups. Conclusions: This is the first study relating LA volumes and function assessed by 2DSTE to MS. 2D speckle tracking analysis of LA volume is relatively easy and provides more detailed information regarding the changes in LA volumes during the cardiac cycle.<\/jats:p>","DOI":"10.1111\/j.1540-8175.2012.01751.x","type":"journal-article","created":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T16:16:45Z","timestamp":1338913005000},"page":"1064-1070","source":"Crossref","is-referenced-by-count":26,"title":["The Impact of Mitral Stenosis on Left Atrial Function Assessed by Two\u2010Dimensional Speckle Tracking 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