{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:36:50Z","timestamp":1777725410705,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,8,17]],"date-time":"2012-08-17T00:00:00Z","timestamp":1345161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>Aims: We assessed impact of pulmonary artery stiffness (<jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content>) on the long\u2010term right ventricular (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>) function and tricuspid regurgitation (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>) changes after percutaneous balloon mitral valvuloplasty (<jats:styled-content style=\"fixed-case\">PBMV<\/jats:styled-content>). Methods and Results: Using <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>oppler echocardiography, <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> was calculated by dividing maximal frequency shift of pulmonary flow by the acceleration time, and mitral area, <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> function, and degree of <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> severity were evaluated before, immediately after, 6\u00a0months, and 12\u00a0months after successful <jats:styled-content style=\"fixed-case\">PBMV<\/jats:styled-content> in 81 consecutive patients. Compared with control subjects patients with mitral stenosis (<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>) had significant higher <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> (P\u00a0&lt;\u00a00.001). The <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> was significantly lower in patients with progressive <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> function improvement and regression of <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> (P\u00a0&lt;\u00a00.001). <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> was significantly correlated with the degree of pulmonary artery systolic pressure (<jats:styled-content style=\"fixed-case\">PASP<\/jats:styled-content>), tricuspid annular plane systolic excursion (<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>), and E\/E'm ratio (P\u00a0&lt;\u00a00.0001, &lt;0.0001, and\u00a0&lt;\u00a00.001, respectively). Multivariate regression analysis showed that the <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> is an independent predictor of <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> regression and sustained <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> functional improvement after successful <jats:styled-content style=\"fixed-case\">PBMV<\/jats:styled-content> (P\u00a0&lt;\u00a00.0001). Conclusions: The changes in <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> function and <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> after successful <jats:styled-content style=\"fixed-case\">PBMV<\/jats:styled-content> were significantly correlated with the degree of <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content>. Despite a sustained increase in mitral valve area, some patients showed no regression of <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>, and progressive <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> dysfunction suggests a significant role of <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> function and the degree of <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> regression in patients with <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> suggests that <jats:styled-content style=\"fixed-case\">PBMV<\/jats:styled-content> must be performed early, utilizing <jats:styled-content style=\"fixed-case\">PAS<\/jats:styled-content> as a noninvasive parameter for proper timing for <jats:styled-content style=\"fixed-case\">PBMV<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/j.1540-8175.2012.01785.x","type":"journal-article","created":{"date-parts":[[2012,8,17]],"date-time":"2012-08-17T07:15:46Z","timestamp":1345187746000},"page":"1157-1163","source":"Crossref","is-referenced-by-count":18,"title":["Impact of Pulmonary Artery Stiffness on Right Ventricular Function and Tricuspid Regurgitation after Successful Percutaneous Balloon Mitral Valvuloplasty: The Importance of Early Intervention"],"prefix":"10.1111","volume":"29","author":[{"given":"Ragab A.","family":"Mahfouz","sequence":"first","affiliation":[{"name":"Cardiology Department Zagazig University Hospital Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,8,17]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1625","volume-title":"Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine","author":"Mann DL","year":"2008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/heart.86.6.715"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.058"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.06.067"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(87)90658-2"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80047-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1183\/09031936.93.02090856","article-title":"Attempts at measuring pulmonary arterial pressure by means of Doppler echocardiography","volume":"2","author":"Torbicki A","year":"1989","journal-title":"Eur Respir J"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.70.2.859"},{"key":"e_1_2_6_10_1","first-page":"92","article-title":"Normal ventricular ejection dynamics in man during rest and exercise","volume":"46","author":"Murgo JP","year":"1975","journal-title":"Am Heart Assoc Monogr"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90295-1"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.09.036"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2011.01527.x"},{"key":"e_1_2_6_14_1","first-page":"92","article-title":"A new echocardiographic approach in assessing pulmonary vascular bed in patients with congenital heart disease: Pulmonary artery stiffness","volume":"3","author":"G\u00f6rg\u00fcl\u00fc S","year":"2003","journal-title":"Anadolu Kardiyol Derg"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00877-2"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2001.115391"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a014963"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(86)90515-6"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/2045-8932.83446"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.05.017"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.88.6.870"},{"key":"e_1_2_6_22_1","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0022-5223(94)70300-0","article-title":"Significant tricuspid regurgitation does not resolve after percutaneous balloon mitral valvotomy","volume":"108","author":"Sagie A","year":"1994","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_6_23_1","first-page":"867","article-title":"Tricuspid regurgitation. 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