{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:46:03Z","timestamp":1791186363854,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,8,17]],"date-time":"2012-08-17T00:00:00Z","timestamp":1345161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>The aim of this study was to determine the utility of the mitral leaflet separation index (<jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content>), for determining the results of percutaneous mitral commissurotomy (<jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>) in the acute setting, in the cardiac catheterization laboratory. Forty\u2010eight patients undergoing <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content> were studied and 96 examinations were performed. The overall correlation with the <jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content> was 0.95. The mitral valve area (<jats:styled-content style=\"fixed-case\">MVA<\/jats:styled-content>) was determined by 2D echo planimetry (<jats:styled-content style=\"fixed-case\">MVA<jats:sub>PLM<\/jats:sub><\/jats:styled-content>) and 0.83 of the <jats:styled-content style=\"fixed-case\">MVA<\/jats:styled-content> was derived using Gorlin's formula (<jats:styled-content style=\"fixed-case\">MVA<jats:sub>GOR<\/jats:sub><\/jats:styled-content>). The <jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content> was significantly different in patients with severe mitral stenosis (<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>) (<jats:styled-content style=\"fixed-case\">MVA<jats:sub>PLM<\/jats:sub><\/jats:styled-content> &lt;1\u00a0cm<jats:sup>2<\/jats:sup>, <jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content> of 0.70\u00a0mm) compared with those with mild <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">MVA<jats:sub>PLM<\/jats:sub><\/jats:styled-content> &gt;1.5\u00a0cm<jats:sup>2<\/jats:sup>, <jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content> of 0.92\u00a0mm). The <jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content> is a simple and effective method for assessment of the <jats:styled-content style=\"fixed-case\">MVA<\/jats:styled-content>. An <jats:styled-content style=\"fixed-case\">MLSI<\/jats:styled-content> &gt;0.92, immediately after <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>, had an excellent sensitivity and specificity for the prediction of an effective <jats:styled-content style=\"fixed-case\">MVA<\/jats:styled-content> of &gt;1.5\u00a0cm<jats:sup>2<\/jats:sup>.<\/jats:p>","DOI":"10.1111\/j.1540-8175.2012.01787.x","type":"journal-article","created":{"date-parts":[[2012,8,17]],"date-time":"2012-08-17T07:21:46Z","timestamp":1345188106000},"page":"1143-1148","source":"Crossref","is-referenced-by-count":9,"title":["The Mitral Leaflet Separation Index for Assessment of Mitral Stenosis during Percutaneous Mitral Commissurotomy: Validation of the Index in the Immediate Post\u2010<scp>PMC<\/scp> Period"],"prefix":"10.1111","volume":"29","author":[{"given":"Bhanu","family":"Duggal","sequence":"first","affiliation":[{"name":"Department of Cardiology Grant Medical College &amp; Sir JJ Hospital Group Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukund","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Department of Cardiology Grant Medical College &amp; Sir JJ Hospital Group Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandesh","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Grant Medical College &amp; Sir JJ Hospital Group Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Cardiology Grant Medical College &amp; Sir JJ Hospital Group Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,8,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1001\/jama.1993.03510140091035","article-title":"Percutaneous mitral balloon valvotomy and the new demographics of mitral stenosis","volume":"270","author":"Carroll JD","year":"1993","journal-title":"JAMA"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-88-3-337"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.05.015"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0742-2822.2004.03057.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl206"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(88)80005-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1979.03630410012009"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.07.012"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2007.02.024"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810330404"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.1999.tb00128.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.51.5.827"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2006.02.007"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.09.041"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810330405"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8175.2012.01787.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8175.2012.01787.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T05:31:41Z","timestamp":1698730301000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8175.2012.01787.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,17]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1111\/j.1540-8175.2012.01787.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8175.2012.01787.x","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,17]]}}}