{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:53:32Z","timestamp":1761058412895},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,2,15]],"date-time":"2006-02-15T00:00:00Z","timestamp":1139961600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p> <jats:italic>We describe the case of an 86\u2010year\u2010old woman who presented with unstable angina. She was given heparin and eptifibatide, and she underwent percutaneous coronary intervention (PCI). Shortly thereafter, she developed acute profound thrombocytopenia (6,000 platelets\/mm<jats:sup>3<\/jats:sup>), which resolved after the discontinuation of heparin and eptifibatide. Four months later, she presented again with unstable angina and underwent PCI. Soon after the procedure, she again developed acute profound thrombocytopenia (2,000 platelets\/mm<jats:sup>3<\/jats:sup>). To our knowledge, acute profound thrombocytopenia due to eptifibatide treatment in the same patient at two different times has not been reported before.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1540-8183.2006.00112.x","type":"journal-article","created":{"date-parts":[[2006,2,15]],"date-time":"2006-02-15T16:28:23Z","timestamp":1140020903000},"page":"99-103","source":"Crossref","is-referenced-by-count":5,"title":["Recurrent Acute Profound Thrombocytopenia Related to Readministration of Eptifibatide"],"prefix":"10.1111","volume":"19","author":[{"given":"AAMIR ADNAN","family":"CHEEMA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANDREW HENRY","family":"TEKLINSKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VIQAR","family":"MARIA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KARUNA","family":"CHILUKURI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOHN JOSEPH","family":"FRANK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARC OLIVER","family":"GOSSELIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00252-6"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)10452-9"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199706123362401"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0140-6736(98)06113-3","article-title":"Randomised placebo\u2010controlled and balloon\u2010angioplasty\u2010controlled trial to assess safety of coronary stenting with use of platelet glycoprotein\u2010IIb\/IIIa blockade. 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