{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T04:36:06Z","timestamp":1715574966988},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,3,24]],"date-time":"2010-03-24T00:00:00Z","timestamp":1269388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p> <jats:italic>\n            <jats:bold>Background:<\/jats:bold> Risk of mortality following an ST\u2010elevation myocardial infarction (STEMI) can be significantly reduced by prompt percutaneous coronary intervention (PCI). National guidelines specify primary PCI as the preferred recommended treatment for STEMI. In this study, we examined same\u2010day PCI as an independent predictor of in\u2010hospital mortality, after adjustment for comorbidities, other patient factors, and hospital PCI\u2010volume using unselected surveillance data from Florida.<\/jats:italic> <\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Methods:<\/jats:bold> We analyzed hospital discharge data for adults, 18+ years old, with a primary diagnosis of STEMI who were admitted to PCI\u2010capable hospitals through the emergency department during 2001\u20132005 (n = 43,849). Hierarchical (multilevel) logistic regression models were used for analysis.<\/jats:italic> <\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Results:<\/jats:bold> Overall, 4,143 STEMI patients (9.4%) did not survive to hospital discharge. In late 2005, the in\u2010hospital mortality rates were 1.9% for those who received same\u2010day PCI versus 13.0% for those who did not. After adjustment for multiple patient factors, same\u2010day PCI was a significant predictor of in\u2010hospital survival with a strong protective effect (adjusted OR = 0.35, 95% CI 0.31\u20130.38 P &lt; 0.0001). Restriction of the analysis to those patients who survived the first day of admission did not appreciably change this result (adjust OR = 0.37, 95% CI 0.33\u20130.42, P &lt; 0.0001). Hospital PCI\u2010volume did not significantly impact mortality risk.<\/jats:italic> <\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Conclusions:<\/jats:bold> Same\u2010day PCI markedly reduced the risk of in\u2010hospital mortality among STEMI patients after multivariate adjustment. Serious comorbidities and complications, older age, and female gender continued to predict elevated risk of mortality after control for treatment status. Our results provide additional evidence in support of national clinical recommendations and aggressive treatment of STEMI.<\/jats:italic> (J Interven Cardiol 2010;23:205\u2013215)<\/jats:p>","DOI":"10.1111\/j.1540-8183.2010.00541.x","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T04:45:35Z","timestamp":1269492335000},"page":"205-215","source":"Crossref","is-referenced-by-count":5,"title":["Percutaneous Coronary Intervention, Comorbidities, and Mortality among Emergency Department\u2013Admitted ST\u2010Elevation Myocardial Infarction Patients in Florida"],"prefix":"10.1111","volume":"23","author":[{"given":"ELIZABETH BARNETT","family":"PATHAK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOEL A.","family":"STROM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,6,3]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"Heart Disease and Stroke Statistics\u20102008 Update","author":"American Heart Association","year":"2008"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMct063503"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12113-7"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000134791.68010.FA"},{"key":"e_1_2_6_6_2","first-page":"296","article-title":"2007 Focused update of the ACC\/AHA 2004 guidelines for the management of patients with ST\u2010elevation myocardial infarction. 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