{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:16:12Z","timestamp":1698970572327},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,12,2]],"date-time":"2010-12-02T00:00:00Z","timestamp":1291248000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:p> <jats:bold>\n            <jats:italic>Background:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>Stent thrombosis is a major complication after percutaneous coronary intervention (PCI) for ST\u2010segment elevation acute myocardial infarction (AMI) and is associated with reinfarction and increased risk of death.<\/jats:italic><\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Methods:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>Patients treated with the turbostratic carbon\u2010coated stent (CID, Saluggia, Italy) for AMI were identified from a prospective primary PCI database. Primary end\u2010point was stent thrombosis within 6 months. Forward stepwise Cox proportional hazards analysis was used to identify independent predictors of stent thrombosis.<\/jats:italic><\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Results:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>Between 2001 and 2008, 746 patients underwent turbostratic carbon\u2010coated stent implantation for AMI. Patients had a mean age of 65 \u00b1 12 years, 9% had cardiogenic shock on admission, 48% had multivessel coronary disease, 78% had baseline target vessel TIMI grade 0\u20131. Multiple stent implantation was performed in 26% of patients. The majority of patients (78%) received abciximab treatment and a postprocedural TIMI grade 3 flow was achieved in 98% patients. Definite stent thrombosis occurred in 10 patients (1.3%), while three patients (0.4%) had possible stent thrombosis. No probable stent thrombosis occurred. There were no procedural stent thromboses. In patients who received abciximab stent thrombosis the rate was 1%, while it was 4.3% in patients not receiving abciximab treatment. After adjusting for all clinical, angiographic, and procedural variables, abciximab treatment (HR 0.17; 95% CI 0.05\u20130.56, P = 0.003) and major bleedings (HR 14.2; 85% CI 2.79\u201372.44, P = 0.001) were the only two predictors related to stent thrombosis.<\/jats:italic><\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Conclusions:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>Patients with AMI treated with turbostratic carbon\u2010coated stent implantation and abciximab treatment have a low incidence of stent thrombosis. Abciximab treatment along with major bleeding complications are the only predictors related to stent thrombosis.<\/jats:italic> (J Interven Cardiol 2010;23:554\u2013559)<\/jats:p>","DOI":"10.1111\/j.1540-8183.2010.00564.x","type":"journal-article","created":{"date-parts":[[2010,7,7]],"date-time":"2010-07-07T12:46:26Z","timestamp":1278506786000},"page":"554-559","source":"Crossref","is-referenced-by-count":2,"title":["Predictor of Stent Thrombosis in Patients Treated with Turbostratic Carbon\u2010Coated Stent Implantation for Acute Myocardial 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