{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T16:40:20Z","timestamp":1698684020783},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,10,9]],"date-time":"2011-10-09T00:00:00Z","timestamp":1318118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p><jats:bold>\n            <jats:italic>Background:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>The long\u2010term safety and effectiveness of drug\u2010eluting stents (DES) versus bare metal stents (BMS) in non\u2010ST\u2010segment elevation myocardial infarction (NSTEMI) beyond 2 years after percutaneous coronary intervention (PCI) is unknown.<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Methods:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>We studied 674 NSTEMI patients who underwent successful PCI with DES (n = 323) or BMS (n = 351). The primary study end\u2010points were time to occurrence of death or nonfatal recurrent myocardial infarction (MI), and stent thrombosis (ST). Secondary end\u2010points included time to occurrence of target vessel revascularization (TVR) and any major adverse cardiovascular event (MACE, defined as the composite of death, MI, ST, TVR).<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Results:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>The DES and BMS groups were well matched except that DES patients received dual antiplatelet therapy for a longer duration and had smaller final vessel diameter. In survival analysis, at a mean follow\u2010up of 1333 \u00b1 659 days after PCI, the DES group had similar incidence of death\/myocardial infarction (24% vs. 27%, log rank p = 0.23) and ST (4.0% vs. 2.6%, p = 0.18) as the BMS group. The DES patients had lower incidence of TVR (8.1% vs. 17%, p = 0.0018) but similar MACE (26% vs. 37%, p = 0.31). In multivariable analysis, DES vs. BMS implantation showed no significant impact on death\/myocardial infarction [adjusted hazards ratio (HR) 1.0, 95% confidence intervals (CI) 0.7\u20131.4], ST (HR 1.7; CI 0.7\u2003\u2013\u20034.0), or MACE (HR 0.8; CI 0.6\u2003\u2013\u20031.1). However, TVR was lower in the DES group (HR 0.4; CI 0.3\u2003\u2013\u20030.7).<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Conclusion:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>In patients presenting with NSTEMI, DES implantation appears to be as safe as BMS implantation at long\u2010term follow\u2010up. In addition, DES are effective in reducing TVR compared to BMS.<\/jats:italic> (J Interven Cardiol 2012;25:28\u201336)<\/jats:p>","DOI":"10.1111\/j.1540-8183.2011.00677.x","type":"journal-article","created":{"date-parts":[[2011,10,10]],"date-time":"2011-10-10T16:17:09Z","timestamp":1318263429000},"page":"28-36","source":"Crossref","is-referenced-by-count":5,"title":["Long\u2010Term Safety and Effectiveness of Drug\u2010Eluting Stents Compared to Bare Metal Stents following Successful PCI in Non\u2010ST\u2010Elevation Myocardial Infarction: Findings from the Guthrie Health Off\u2010Label StenT (GHOST) Registry"],"prefix":"10.1111","volume":"25","author":[{"given":"KISHORE 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Angina\/Non\u2010ST\u2010Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine","volume":"50","author":"Anderson JL","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.05.015"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.074"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801485"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.826479"},{"issue":"2","key":"e_1_2_7_7_2","doi-asserted-by":"crossref","first-page":"c57\u2013c73","DOI":"10.3909\/ricm0517","article-title":"Safety and efficacy of drug\u2010eluting stents 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