{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:15:51Z","timestamp":1783426551122,"version":"3.54.6"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T00:00:00Z","timestamp":1323648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Interven Cardiology"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p><jats:bold>\n            <jats:italic>Objectives:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>To evaluate the association between N\u2010terminal pro\u2010B\u2010type natriuretic peptide (NT\u2010proBNP) values and the severity of coronary lesions at angiography in unstable angina patients with preserved left ventricular function.<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Methods:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>A total of 133 patients with primary diagnosis of unstable angina were enrolled into this study. NT\u2010proBNP level was determined before the angiography and Gensini score, a measurement of extent of myocardial ischemia, was calculated after the angiography by experienced cardiologists. Patients with &gt;50% stenosis of the left main or 75% stenosis of one or more coronary branches with diameter &gt;2 mm were defined as \u201cangiography positive\u201d and turned to percutaneous coronary intervention.<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Results:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>There was a significant difference of circulating NT\u2010proBNP level between the angiography positive and negative groups and the median NT\u2010proBNP values were 367.5 pg\/mL and 112 pg\/mL, respectively (P &lt; 0.001). A significant correlation was observed between log NT\u2010proBNP and log Gensini score (P &lt; 0.001). NT\u2010proBNP level was a predictor of angiography positive result and the area under the receiver operating characteristic curve was 0.776 (95% CI 0.693\u20130.858).<\/jats:italic><\/jats:p><jats:p><jats:bold>\n            <jats:italic>Conclusions:<\/jats:italic>\n          <\/jats:bold>\u2002<jats:italic>NT\u2010proBNP level was found to be higher with the severity of myocardial ischemia. However, the ability of NT\u2010proBNP to identify clinically significant angiographic lesions was moderate.<\/jats:italic> (J Interven Cardiol 2012;25:126\u2013131)<\/jats:p>","DOI":"10.1111\/j.1540-8183.2011.00697.x","type":"journal-article","created":{"date-parts":[[2011,12,13]],"date-time":"2011-12-13T04:04:14Z","timestamp":1323749054000},"page":"126-131","source":"Crossref","is-referenced-by-count":8,"title":["N\u2010Terminal Pro\u2010B\u2010Type Natriuretic Peptide is Associated with Severity of the Coronary Lesions in Unstable Angina Patients with Preserved Left Ventricular Function"],"prefix":"10.1111","volume":"25","author":[{"given":"GAO","family":"WEI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WANG","family":"NINGFU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YE","family":"XIANHUA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZHOU","family":"LIANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YANG","family":"JIANMIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TONG","family":"GUOXIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XU","family":"PENG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,12,12]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2008.08.005"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0796fje"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011053"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.12.020"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.02.003"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/17482940802100261"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(83)80105-2"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.03-1336fje"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2006.101303"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.071423"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.02.003"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/17482940802100261"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.1.82"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1999.2045"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000147611.92021.2B"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.057"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01986-1"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.04.085"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq468"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.11.054"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00168-2"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.03.072"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-8183.2011.00697.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-8183.2011.00697.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T11:32:52Z","timestamp":1698665572000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-8183.2011.00697.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,12]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1111\/j.1540-8183.2011.00697.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-8183.2011.00697.x","archive":["Portico"],"relation":{},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"value":"0896-4327","type":"print"},{"value":"1540-8183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,12]]}}}