{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T22:11:57Z","timestamp":1697062317430},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T00:00:00Z","timestamp":1182384000000},"content-version":"vor","delay-in-days":1146,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skinmed"],"published-print":{"date-parts":[[2004,5]]},"abstract":"A 21\u2010year\u2010old man presented with the complaint of vertex pattern alopecia for the last 14 years after a sudden hair loss due to alopecia areata totalis 15 years ago. He was in otherwise good health and denied using any medication. Teeth and nails were normal. His serum hormone levels and thyroid function profile were within normal limits. Other autoimmune diseases, including systemic lupus erythematosus, vitiligo, and diabetes mellitus were excluded clinically and experimentally. First\u2010degree family had no such background. Potassium hydroxide preparation of plucking hair was negative for fungal hyphae and spores. A final diagnosis of alopecia areata was made. Application of steroid cream at the site of alopecia was effective at first: regrowth hair gradually appeared at the nonandrogenic\u2010dependent region, but remained stagnant for the following 14 years. There were neither symptoms associated with the lesions nor psychosocial disturbances preceding the onset. On examination, a circumscribed U shaped display of hair loss over the center of the scalp, with persistence of hair only at the hair margin, was observed, mimicking grade VII on the Hamilton male\u2010pattern baldness classification system scale (Figure\u20031<\/jats:ext-link> and Figure\u20032<\/jats:ext-link>). Another area affected was identical to the distribution pattern of ophiasis in alopecia areata, which locates at the hair margin of the right temple with an area ranging 4 cm in diameter (Figure\u20033<\/jats:ext-link>). There was no clinical evidence of inflammation. Exclamation point hair was invisible. Differential diagnoses to be considered May include trichotillomania, circumscribed scleroderma, congenital vertical alopecia, aplasia cutis congenital, and familial focal alopecia. All of these conditions might be ruled out on the basis of the patient's history and clinical findings.<\/jats:p> A circumscribed<\/jats:italic> U\u2010shaped display of hair loss is over the center of the scalp, with persistence of hair only at the hair margin, mimicking grade VII male\u2010pattern baldness on the Hamilton scale<\/jats:italic><\/jats:p><\/jats:caption>image<\/jats:alt-text><\/jats:graphic><\/jats:fig><\/jats:p> Illustration of the Hamilton male\u2010pattern baldness classification system scale<\/jats:italic> <\/jats:p><\/jats:caption>image<\/jats:alt-text><\/jats:graphic><\/jats:fig><\/jats:p> Another area affected has a distribution just like that seen in ophiasis in alopecia areata, with bald patches located at the hair margin of the right temple with an area ranging about 4 cm in diameter.<\/jats:italic> <\/jats:p><\/jats:caption>image<\/jats:alt-text><\/jats:graphic><\/jats:fig><\/jats:p>","DOI":"10.1111\/j.1540-9740.2004.03253.x","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T12:14:06Z","timestamp":1182428046000},"page":"173-175","source":"Crossref","is-referenced-by-count":1,"title":["Mosaic Hair Regrowth Pattern of Ophiasis and Androgenic Alopecia in a Patient With Alopecia Areata Totalis"],"prefix":"10.1111","volume":"3","author":[{"given":"Cheng","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Wuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,6,21]]},"reference":[{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.132.10.1255"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.8.1042"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1968.tb11960.x"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.133.1.114"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsp.5640214"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2370.2002.00271.x"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.2340\/0001555576421423"}],"container-title":["SKINmed: Dermatology for the Clinician"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1540-9740.2004.03253.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-9740.2004.03253.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/j.1540-9740.2004.03253.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1540-9740.2004.03253.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T22:22:41Z","timestamp":1694384561000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1540-9740.2004.03253.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["10.1111\/j.1540-9740.2004.03253.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1540-9740.2004.03253.x","archive":["Portico"],"relation":{},"ISSN":["1540-9740","1751-7125"],"issn-type":[{"value":"1540-9740","type":"print"},{"value":"1751-7125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}