{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T09:44:37Z","timestamp":1778579077529,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T00:00:00Z","timestamp":1182211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skinmed"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p> <jats:bold>\n            <jats:italic>Background.<\/jats:italic>\n          <\/jats:bold>\n          <jats:italic>The treatment of verrucae with bleomycin injections has not become a routinely adopted form of therapy in dermatologic practice since its use was originally described in 1980 because of the adverse effects and complications that have been associated with it.<\/jats:italic> <\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Objectives.<\/jats:italic>\n          <\/jats:bold>\n          <jats:italic>The goal of this study was to demonstrate the results and the incidence of adverse effects from the use of bleomycin in clinical practice in a retrospective study of patients presenting with verrucae and to demonstrate the convenience and ease of the methodology that was used in obtaining these results.<\/jats:italic> <\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Methods.<\/jats:italic>\n          <\/jats:bold>\n          <jats:italic>Patients' lesions were injected with bleomycin every 3 to 4 weeks until the lesions had been eliminated or the injections were discontinued because of adverse effects or complications.<\/jats:italic> <\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Results.<\/jats:italic>\n          <\/jats:bold>\n          <jats:italic>There were 211 patients in the study, and 224 lesions were treated. After 1 treatment, 47.6% of the lesions were cleared; another 38.8%were cleared after 2 treatments; and another 9.8% were cleared after 3 treatments. In total, 96% of lesions were cleared after 5 treatments. A small number of temporary adverse effects were noted: 3 patients had local chemical cellulitis, 2 patients had formation of sterile abscesses, 1 patient had postinflammatory hyperpigmentation, and 1 patient had localized pain. No local or systemic complications were observed.<\/jats:italic> <\/jats:p><jats:p> <jats:bold>\n            <jats:italic>Conclusions.<\/jats:italic>\n          <\/jats:bold>\n          <jats:italic>Therapy with intralesional bleomycin is a relatively rapid and convenient form of therapy, compared with other available treatments, from the point of view of both the patient and the physician.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1540-9740.2007.06451.x","type":"journal-article","created":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T14:30:50Z","timestamp":1182263450000},"page":"166-171","source":"Crossref","is-referenced-by-count":7,"title":["Bleomycin Treatment for Verrucae"],"prefix":"10.1111","volume":"6","author":[{"given":"Norman M.","family":"Price","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,7,2]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"445","article-title":"Report on the treatment of verrucosis with local injection of bleomycin. 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