{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:40:38Z","timestamp":1790790038307,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2011,10,9]],"date-time":"2011-10-09T00:00:00Z","timestamp":1318118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biometrics"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p><jats:bold><jats:sc>Summary<\/jats:sc><\/jats:bold> A novel point process model continuous in space\u2013time is proposed for quantifying the transmission dynamics of the two most common meningococcal antigenic sequence types observed in Germany 2002\u20132008. Modeling is based on the conditional intensity function (CIF), which is described by a superposition of additive and multiplicative components. As an epidemiological interesting finding, spread behavior was shown to depend on type in addition to age: basic reproduction numbers were 0.25 (95% CI 0.19\u20130.34) and 0.11 (95% CI 0.07\u20130.17) for types B:P1.7\u20132,4:F1\u20135 and C:P1.5,2:F3\u20133, respectively. Altogether, the proposed methodology represents a comprehensive and universal regression framework for the modeling, simulation, and inference of self\u2010exciting spatiotemporal point processes based on the CIF. Usability of the modeling in biometric practice is promoted by an implementation in the <jats:styled-content>R<\/jats:styled-content> package <jats:styled-content>surveillance<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/j.1541-0420.2011.01684.x","type":"journal-article","created":{"date-parts":[[2011,10,10]],"date-time":"2011-10-10T16:51:49Z","timestamp":1318265509000},"page":"607-616","source":"Crossref","is-referenced-by-count":71,"title":["A Space\u2013Time Conditional Intensity Model for Invasive Meningococcal Disease Occurrence"],"prefix":"10.1093","volume":"68","author":[{"given":"Sebastian","family":"Meyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Elias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"H\u00f6hle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,10,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csda.2008.10.032"},{"key":"e_1_2_9_3_1","author":"Daley D. 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