{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T18:36:25Z","timestamp":1774118185108,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T00:00:00Z","timestamp":1161907200000},"content-version":"vor","delay-in-days":1579,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:p><jats:bold>Background: <\/jats:bold> Supraventricular tachyarrhythmia is a common problem in chronic obstructive pulmonary disease (COPD) patients. The purpose of this study is to analyze the factors associated with paroxysmal atrial fibrillation (AF) in COPD patients.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> Forty COPD patients (38 male, 2 female, mean age 60 \u00b1 9 years) and 33 healthy controls (29 male, 4 female, mean age: 58 \u00b1 10 years) were included in this study. Echocardiography, 24\u2010hour ambulatory and 12\u2010lead ECG, pulmonary function tests, arterial blood gases, and serum electrolytes were measured. On ECG, maximum (P<jats:sub>max<\/jats:sub>) and minimum (P<jats:sub>min<\/jats:sub>) duration of P wave and its difference, P\u2010wave dispersion (PWd), were measured.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> On echocardiography, diastolic dysfunction was found in 14 of the 40 (35%) COPD patients. Heart rate variability analysis revealed that COPD patients had decreased SDANN, SDNN, SDNNIDX in time\u2010domain, and decreased LF in frequency domain parameters. Fourteen of the 40 COPD patients (35%) had AF. Patients with AF were older (57 \u00b1 10 vs 64 \u00b1 5 years, P = 0.03) and had lower SDANN, SDNN, and LF\/HF ratio as compared to patients without AF in univariate analysis. All P\u2010wave intervals (P<jats:sub>max<\/jats:sub> P<jats:sub>min<\/jats:sub> and PWd) were increased in COPD patients compared to controls. P\u2010wave dispersion was significantly increased in COPD patients with AF, as compared to patients without AF (57 \u00b1 11 vs 44 \u00b1 7 ms, P = 0.001). In logistic regression analysis PWd was found to be the only factor associated with the development of AF (P = 0.04).<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> The presence of AF was significantly related to the prolongation of PWd, but not with pulmonary function, arterial blood gasses, and left and right atrial function. <jats:bold>A.N.E. 2002;7(3):222\u2013227<\/jats:bold><\/jats:p>","DOI":"10.1111\/j.1542-474x.2002.tb00167.x","type":"journal-article","created":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T14:00:54Z","timestamp":1161957654000},"page":"222-227","source":"Crossref","is-referenced-by-count":42,"title":["Factors Associated with the Development of Atrial Fibrillation in COPD Patients: <i>The Role of P\u2010Wave Dispersion<\/i>"],"prefix":"10.1111","volume":"7","author":[{"given":"Tufan","family":"T\u00fckek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinar","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vakur","family":"Akkaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Akif Karan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dursun","family":"Atilgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veysel","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferruh","family":"Korkut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,27]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"43","article-title":"Causes of death in patients with COPD and chronic respiratory failure","volume":"52","author":"Zielinski J","year":"1997","journal-title":"Monaldi Arch Chest Dis"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)31109-9"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.94.1.44"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(96)02876-8"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000196340"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.88.4.537"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.91.6.808"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2000.tb06761.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(98)70030-4"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960241008"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2000.tb07038.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(98)00301-5"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.29.2.242"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.54.4.553"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.2.212"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.6.1072"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/14.suppl_D.8"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.55.4.613"},{"key":"e_1_2_1_20_2","unstructured":"Circulation 1996 93 Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. 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