{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:21:46Z","timestamp":1791919306148,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,6,28]],"date-time":"2006-06-28T00:00:00Z","timestamp":1151452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p> <jats:italic>Background and Purpose.<\/jats:italic> Endovascular treatment for intracranial atherosclerosis is evolving, but complications remain an issue. Most interventions are performed under general anesthesia, preventing intraprocedural clinical evaluations. We describe our approach to intracranial angioplasty and stenting, using local rather than general anesthesia, and intraprocedural neurological assessment.<\/jats:p><jats:p> <jats:italic>Methods.<\/jats:italic> We prospectively collected procedural and outcome information on all patients undergoing intracranial angioplasty and stenting. Patients underwent interventions under local anesthesia with mild intravenous sedation or analgesia only if needed. Intraoperative neurological evaluations were performed, and symptomatology was used to guide the interventional technique.<\/jats:p><jats:p> <jats:italic>Results.<\/jats:italic> Forty\u2010eight arteries in 40 patients with a mean age of 65.2 years were treated. Thirty\u2010two anterior and 16 posterior circulation segments were treated. Technical success was achieved in 100% of patients with reduction of the mean pretreatment stenosis from 85 \u00b1 8.6% to 7 \u00b1 10.1%. Stents were deployed in 40 segments; five patients were treated with drug\u2010eluting stents. The cobalt\u2010chromium coronary stents were the easiest to deliver. Thirty\u2010seven patients were treated under local anesthesia and, of those, 61.4% experienced intraprocedural symptoms that led to some alteration of the interventional technique. Headache was the most common symptom, and, when persistent, it heralded the occurrence of subarachnoid hemorrhage. There were seven total neurological complications, but only five (10.5%) led to permanent morbidity (4 strokes) or mortality (1 death).<\/jats:p><jats:p> <jats:italic>Conclusions.<\/jats:italic> Intracranial angioplasty and stenting can be successfully performed using coronary techniques and equipment including drug\u2010eluting stents. Local anesthesia permits neurological evaluations and often leads to the adjustment of the interventional technique, potentially making the procedure safer.<\/jats:p>","DOI":"10.1111\/j.1552-6569.2006.00043.x","type":"journal-article","created":{"date-parts":[[2009,10,5]],"date-time":"2009-10-05T13:59:11Z","timestamp":1254751151000},"page":"216-223","source":"Crossref","is-referenced-by-count":61,"title":["Intracranial Angioplasty and Stenting in the Awake Patient"],"prefix":"10.1111","volume":"16","author":[{"given":"Alex","family":"Abou\u2010Chebl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derk W.","family":"Krieger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher T.","family":"Bajzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay S.","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,6,28]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.1.14"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043033"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/jon199774232"},{"issue":"9","key":"e_1_2_7_5_2","first-page":"1661","article-title":"Intracranial angioplasty: Experience and complications","volume":"18","author":"Takis C","year":"1997","journal-title":"AJNR Am J Neuroradiol"},{"issue":"8","key":"e_1_2_7_6_2","first-page":"1525","article-title":"Follow\u2010up study after intracranial percutaneous transluminal cerebral balloon angioplasty","volume":"19","author":"Mori T","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.3.0415"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.5.1065"},{"issue":"9","key":"e_1_2_7_9_2","first-page":"1688","article-title":"Intracranial deployment of coronary stents for symptomatic atherosclerotic disease","volume":"20","author":"Morris PP","year":"1999","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.11.1625"},{"key":"e_1_2_7_11_2","first-page":"249","article-title":"Short\u2010term arteriographic and clinical outcome after cerebral angioplasty and stenting for intracranial vertebrobasilar and carotid atherosclerotic occlusive disease","volume":"21","author":"Mori T","year":"2000","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2000.92.5.0771"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200106000-00002"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1101"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000103900.65021.5B"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000130846.46168.03"},{"issue":"1","key":"e_1_2_7_17_2","first-page":"294","article-title":"Long\u2010term outcome in symptomatic intracranial vertebrobasilar occlusive disease","volume":"31","author":"Abou\u2010Chebl A","year":"2000","journal-title":"Stroke"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.4.490"},{"issue":"2","key":"e_1_2_7_19_2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S1042-3680(18)30133-5","article-title":"Carotid endarterectomy using regional anesthesia","volume":"11","author":"Harbaugh RE","year":"2000","journal-title":"Neurosurg Clin N Am"},{"issue":"5","key":"e_1_2_7_20_2","first-page":"787","article-title":"Cerebral angioplasty and stenting for intracranial vertebral atherosclerotic stenosis","volume":"20","author":"Mori T","year":"1999","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00333054"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1552-6569.2006.00043.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1552-6569.2006.00043.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T02:33:34Z","timestamp":1696991614000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1552-6569.2006.00043.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,28]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["10.1111\/j.1552-6569.2006.00043.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1552-6569.2006.00043.x","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,28]]}}}