{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:16:22Z","timestamp":1791850582302,"version":"4.3.4"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T00:00:00Z","timestamp":1354752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The \u201cears of the lynx\u201d sign was previously reported as a neuroimaging finding observed in patients with autosomal recessive hereditary spastic paraplegia in association with a thin corpus callosum (ARHSP\u2013TCC). We report a patient with a chronic form of Marchiafava\u2013Bignami disease (MBD) that presented with this imaging feature. Diffusion tensor imaging (DTI) and fiber\u2010tracking data support that this finding is a consequence of the structural derangement, which enlarges a preexisting border zone of the bundles of fibers from the corpus callosum (CC) genu to the forceps minor and anterior corona radiata. Therefore, we assume that despite their pathological differences, damage to the anterior portion of the CC is responsible for the imaging similarities between MBD and ARHSP\u2013TCC.<\/jats:p>","DOI":"10.1111\/j.1552-6569.2012.00714.x","type":"journal-article","created":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T20:43:23Z","timestamp":1354826603000},"page":"205-207","source":"Crossref","is-referenced-by-count":15,"title":["\u201cEars of the Lynx\u201d Sign in a Marchiafava\u2013Bignami patient: Structural Basis and Fiber\u2010Tracking DTI Contribution to the Understanding of this Imaging Abnormality"],"prefix":"10.1111","volume":"24","author":[{"given":"Felipe Torres","family":"Pacheco","sequence":"first","affiliation":[{"name":"Division of Neuroradiology Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena Morais","family":"Rego","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurosurgery Hospital Regional do Vale do Ribeira, Pariquera\u2010A\u00e7u \u2013 SP  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Iram Mendon\u00e7a","family":"do Rego","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurosurgery Hospital Regional do Vale do Ribeira, Pariquera\u2010A\u00e7u \u2013 SP  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio J.","family":"da Rocha","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,6]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2008.00327.x"},{"key":"e_1_2_4_3_1","volume-title":"MRI Atlas of Human White Matter","author":"Mori S","year":"2004"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2006.00041.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMicm030414"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2001.00212.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-004-0566-1"},{"issue":"3","key":"e_1_2_4_8_1","first-page":"670","article-title":"Cortical involvement in Marchiafava\u2010Bignami disease","volume":"26","author":"Johkura K","year":"2005","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050702"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1897"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2301021640"},{"issue":"7","key":"e_1_2_4_12_1","first-page":"1249","article-title":"Regional cerebral glucose metabolism and blood flow in a patient with Marchiafava\u2010Bignami disease","volume":"20","author":"Ishii K","year":"1999","journal-title":"Am J Neuroradiol"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1552-6569.2012.00714.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1552-6569.2012.00714.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T20:40:48Z","timestamp":1696279248000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1552-6569.2012.00714.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,6]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/j.1552-6569.2012.00714.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1552-6569.2012.00714.x","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,6]]}}}