{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:16:43Z","timestamp":1760955403185},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,10]],"date-time":"2012-12-10T00:00:00Z","timestamp":1355097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuroimaging"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Vertebral artery dissection (VAD) is one of the most important etiologies in young stroke patients. VAD causes ischemic stroke by embolism and transcranial Doppler (TCD) monitoring can detect microemboli originating from the dissection point as high intensity transient signals (HITS). We developed a simple but novel method of TCD monitoring at the vertebrobasilar junction in VAD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>We placed a Welder TCD headband upside down on the patient's head and rotated it by 90\u00b0. Then we fixed a pulsed\u2010wave 2\u2010MHz TCD probe to the headband and put it on the suboccipital paramedian area of the patient. With a patient in the lateral decubitus position, the vertebrobasilar junction was identified at a depth of approximately 80 mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>We examined 11 patients with VAD and detected HITS in 2 patients (18%). In 1 patient HITS disappeared after heparinization, and in the other patient HITS disappeared after treatment with aspirin. All of 9 HITS\u2010negative patients and 1 of 2 HITS\u2010positive patients experienced no ischemic recurrence during hospitalization.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>We successfully detected HITS at the vertebrobasilar junction in VAD patients, which may lead not only to an appropriate choice of antithrombotic drugs but also to individual evaluation of early risk of ischemic recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1552-6569.2012.00749.x","type":"journal-article","created":{"date-parts":[[2012,12,10]],"date-time":"2012-12-10T20:55:46Z","timestamp":1355172946000},"page":"191-194","source":"Crossref","is-referenced-by-count":15,"title":["A Novel Method for Transcranial Doppler Microembolic Signal Monitoring at the Vertebrobasilar Junction in Vertebral Artery Dissection Patients"],"prefix":"10.1111","volume":"24","author":[{"given":"Y.","family":"Yamaoka","sequence":"first","affiliation":[{"name":"Stroke Center NTT Medical Center Tokyo  Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"Stroke Center NTT Medical Center Tokyo  Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery NTT Medical Center Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Sameshima","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery NTT Medical Center Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ochiai","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery NTT Medical Center Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery NTT Medical Center Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,10]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"203","article-title":"Clinical features and current status of diagnosis and management of vertebrobasilar artery dissections in Japan","volume":"54","author":"Takagi M","year":"2002","journal-title":"No to Shinkei"},{"key":"e_1_2_5_3_1","first-page":"881","article-title":"Analysis of ischemic stroke in patients aged up to 50 years","volume":"40","author":"Yonemura K","year":"2000","journal-title":"Clin Neurol"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182012323"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.489666"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000047662"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.11.1738"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199774217"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.7.1226"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2001.tb00013.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2007.00109.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.6.1335"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.3.725"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.6.1123"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000047701"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.3.593"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.487454"}],"container-title":["Journal of Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1552-6569.2012.00749.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1552-6569.2012.00749.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T20:41:53Z","timestamp":1696279313000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1552-6569.2012.00749.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,10]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/j.1552-6569.2012.00749.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1552-6569.2012.00749.x","archive":["Portico"],"relation":{},"ISSN":["1051-2284","1552-6569"],"issn-type":[{"value":"1051-2284","type":"print"},{"value":"1552-6569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,10]]}}}