{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T07:26:14Z","timestamp":1791962774025,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,1,31]],"date-time":"2007-01-31T00:00:00Z","timestamp":1170201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p><jats:bold>ABSTRACT: <\/jats:bold> Prediction of physical appearance based on genetic analysis is a very attractive prospect for forensic investigations. Recent studies have proved that there is a significant association between some genetic variants of the melanocortin 1 receptor (MC1R) gene and red hair color. The present study focuses on the potential forensic applicability of variation within this pigment\u2010related gene. Sequencing of the complete MC1R gene was performed on a group of red\u2010haired individuals and controls with different pigmentation. A major role in determination of red hair color is played by two MC1R variants\u2014C451T and C478T. The optimized minisequencing assay for genotyping of the above positions and three other important red hair\u2010related MC1R polymorphisms, C252A, G425A, and G880C was successfully applied to analyze typical forensic specimens. Determination of a homozygous or heterozygous combination can be a good predictor of both red hair color and fair skin of a subject.<\/jats:p>","DOI":"10.1111\/j.1556-4029.2006.00361.x","type":"journal-article","created":{"date-parts":[[2007,2,2]],"date-time":"2007-02-02T21:58:45Z","timestamp":1170453525000},"page":"349-354","source":"Crossref","is-referenced-by-count":58,"title":["Determination of Phenotype Associated SNPs in the MC1R Gene<sup>*<\/sup>"],"prefix":"10.1111","volume":"52","author":[{"given":"Wojciech","family":"Branicki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urszula","family":"Brudnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Kupiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Wola\u00f1ska\u2010Nowak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Wojas\u2010Pelc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,31]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0504-431"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0027-5107(03)00014-9"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/35057062"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature03001"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1403"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1520\/JFS2002079"},{"key":"e_1_2_7_8_2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00439-002-0896-y","article-title":"Skin pigmentation, biogeographical ancestry and admixture mapping","volume":"112","author":"Shriver MD","year":"2003","journal-title":"Hum Genet"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrfmmm.2004.09.014"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/425285"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/302863"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.9253"},{"key":"e_1_2_7_13_2","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1158\/1055-9965.808.13.5","article-title":"Assessment of polymorphic variants in the melanocortin\u20101 receptor gene with cutaneous pigmentation using an evolutionary approach","volume":"13","author":"Kanetsky PA","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"e_1_2_7_14_2","unstructured":"SPSS Inc. http:\/\/www.spss.pl"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0379-0738(01)00480-7"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb03199.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0000027"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi219"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genet.37.110801.143233"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/509"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/339076"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.17.2531"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1004(1997)9:1<30::AID-HUMU5>3.0.CO;2-T"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.11.1891"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0379-0738(03)00299-8"}],"container-title":["Journal of Forensic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1556-4029.2006.00361.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1556-4029.2006.00361.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T03:14:32Z","timestamp":1697339672000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1556-4029.2006.00361.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,31]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1111\/j.1556-4029.2006.00361.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1556-4029.2006.00361.x","archive":["Portico"],"relation":{},"ISSN":["0022-1198","1556-4029"],"issn-type":[{"value":"0022-1198","type":"print"},{"value":"1556-4029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,31]]}}}