{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T06:01:50Z","timestamp":1791093710825,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,9,25]],"date-time":"2012-09-25T00:00:00Z","timestamp":1348531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 20\u2010year\u2010old man, a cocaine addict and regular ecstasy user, with a medical history of allergic asthma died after ingesting half a tablet earlier the same day. The white tablet, stamped with a \u201csmiling sun\u201d logo looked very much like an ecstasy tablet and was sold as such. He experienced a severe asthma attack just after ingesting the half tablet and it evolved over the next few hours into fatal cardiorespiratory arrest. Biological samples, taken after embalming, were analyzed by high\u2010performance liquid chromatography tandem mass spectrometry (<jats:styled-content style=\"fixed-case\">HPLC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MS\/MS<\/jats:styled-content>). Analysis revealed meta\u2010chlorophenylpiperazine (<jats:styled-content style=\"fixed-case\">mCPP<\/jats:styled-content>) in concentrations of 45.8\u00a0mg in a similar tablet obtained later from the drug dealer, 5.1\u00a0ng\/mL in the bile, 0.3\u00a0ng\/g in the liver, 15.0\u00a0ng\/mL in the urine, and its absence in a hair sample (&lt;0.02\u00a0ng\/mg), which indicated he was not a regular user (whereas strong concentrations of <jats:styled-content style=\"fixed-case\">MDMA<\/jats:styled-content> and cocaine were found in the hair). Interrogated by the police after his arrest, the dealer said that he had sold the victim and for the very first time two tablets with the same \u201csmiling sun\u201d logo. The tablet used for analysis was from the same brand as the one ingested by the victim. The autopsy excluded other causes of death, while the histological analyses showed a large number of polynuclear eosinophils in the bronchial walls, confirming the asthmatic pathology. None of the other organs examined (larynx, liver, heart, adrenal glands, and kidneys) showed any distinctive signs, and in particular no inflammatory infiltrate. The death was the result of an asthma attack in an asthmatic person, violently decompensated following ingestion of approximately 20\u00a0mg of <jats:styled-content style=\"fixed-case\">mCPP<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/j.1556-4029.2012.02254.x","type":"journal-article","created":{"date-parts":[[2012,9,26]],"date-time":"2012-09-26T06:28:32Z","timestamp":1348640912000},"page":"263-269","source":"Crossref","is-referenced-by-count":33,"title":["A Fatality Following Ingestion of the Designer Drug Meta\u2010Chlorophenylpiperazine (<scp>mCPP<\/scp>) in an Asthmatic\u2014<scp>HPLC\u2010MS\/MS<\/scp> Detection in Biofluids and Hair"],"prefix":"10.1111","volume":"58","author":[{"given":"Yvan P.","family":"Gaillard","sequence":"first","affiliation":[{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 800 Avenue Marie Curie ZI Jean Jaur\u00e8s 07800 La Voulte sur Rh\u00f4ne France"},{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 98 avenue des fr\u00e8res Lumi\u00e8re 69008 Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Claire","family":"Cuquel","sequence":"additional","affiliation":[{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 800 Avenue Marie Curie ZI Jean Jaur\u00e8s 07800 La Voulte sur Rh\u00f4ne France"},{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 98 avenue des fr\u00e8res Lumi\u00e8re 69008 Lyon France"},{"name":"Ecole du Service de Sant\u00e9 des Arm\u00e9es 331 avenue du G\u00e9n\u00e9ral De Gaulle 69500 Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Boucher","sequence":"additional","affiliation":[{"name":"Centre d'Evaluation et d'Information sur la Pharmacod\u00e9pendance 162 A avenue Lacassagne 69424 Lyon Cedex 03 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"Romeuf","sequence":"additional","affiliation":[{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 800 Avenue Marie Curie ZI Jean Jaur\u00e8s 07800 La Voulte sur Rh\u00f4ne France"},{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 98 avenue des fr\u00e8res Lumi\u00e8re 69008 Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Bevalot","sequence":"additional","affiliation":[{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 800 Avenue Marie Curie ZI Jean Jaur\u00e8s 07800 La Voulte sur Rh\u00f4ne France"},{"name":"Laboratory of Analytical Toxicology LAT LUMTOX 98 avenue des fr\u00e8res Lumi\u00e8re 69008 Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jen\u2010Michel","family":"Prevosto","sequence":"additional","affiliation":[{"name":"H\u00f4pital d'Instruction des Arm\u00e9es Desgenettes 108 boulevard Pinel BP25 69998 Lyon Arm\u00e9es France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Marie","family":"Menard","sequence":"additional","affiliation":[{"name":"Cabinet m\u00e9dical 5 avenue du principal Pastour 06602 Antibes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,25]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"European Police Office.Europol\u2013EMCDDA active monitoring report on a new psychoactive substance: 1\u2010(3\u2010chlorophenyl)piperazine (mCPP): Annex 3: legal status. 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