{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:14:53Z","timestamp":1792224893167,"version":"4.4.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1111\/j.1567-1364.2006.00040.x","type":"journal-article","created":{"date-parts":[[2006,2,2]],"date-time":"2006-02-02T09:34:26Z","timestamp":1138872866000},"page":"744-750","source":"Crossref","is-referenced-by-count":143,"title":["The genome-wide screening of yeast deletion mutants to identify the genes required for tolerance to ethanol and other alcohols"],"prefix":"10.1093","volume":"6","author":[{"given":"Katsuhide","family":"Fujita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinobu","family":"Matsuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Iwahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB8","unstructured":"Alexandre H , Plourde L , Charpentier C & Francois J (1998) Lack of correlation between trehalose accumulation, cell viability and intracellular acidification as induced by various stresses in Saccharomycescerevisiae. Microbiology 144: 1103\u00e2\u0080\u00931111."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB28","unstructured":"Alexandre H , Ansanay-Galeote V , Dequin S & Blondin B (2001) Global gene expression during short-term ethanol stress in Saccharomycescerevisiae. FEBS Lett 498: 98\u00e2\u0080\u0093103."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB14","unstructured":"Blackburn AS & Avery SV (2003) Genome-wide screening of Saccharomycescerevisiae to identify genes required for antibiotic insusceptibility of eukaryotes. Antimicrob Agents Chemother 47: 676\u00e2\u0080\u0093681."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB10","unstructured":"Costa V , Amorim MA , Reis E , Quintanilha A & Moradas-Ferreira P (1997) Mitochondrial superoxide dismutase is essential for ethanol tolerance of Saccharomycescerevisiae in the post-diauxic phase. Microbiology 143: 1649\u00e2\u0080\u00931656."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB6","unstructured":"Fujita K , Matsuyama A , Kobayashi Y & Iwahashi H (2004) Comprehensive gene expression analysis of the response to straight-chain alcohols in Saccharomycescerevisiae using cDNA microarray. J Appl Microbiol 97: 57\u00e2\u0080\u009367."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB15","doi-asserted-by":"crossref","unstructured":"Geissler S , Siegers K & Schiebel E (1998) A novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J 17: 952\u00e2\u0080\u0093966.","DOI":"10.1093\/emboj\/17.4.952"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB18","unstructured":"Giaever G , Chu AM , Ni L , et al. (2002) Functional profiling of the Saccharomycescerevisiae genome. Nature 418: 387\u00e2\u0080\u0093391."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB12","doi-asserted-by":"crossref","unstructured":"Higgins VJ , Alic N , Thorpe GW , Breitenbach M , Larsson V & Dawes IW (2002) Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress. Yeast 19: 203\u00e2\u0080\u0093214.","DOI":"10.1002\/yea.811"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB22","doi-asserted-by":"crossref","unstructured":"Ho MN , Hill KJ , Lindorfer MA & Stevens TH (1993a) Isolation of vacuolar membrane H(+)-ATPase-deficient yeast mutants; the VMA5 and VMA4 genes are essential for assembly and activity of the vacuolar H(+)-ATPase. J Biol Chem 268: 221\u00e2\u0080\u0093227.","DOI":"10.1016\/S0021-9258(18)54138-7"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB23","doi-asserted-by":"crossref","unstructured":"Ho MN , Hirata R , Umemoto N , Ohya Y , Takatsuki A , Stevens TH & Anraku Y (1993b) VMA13 encodes a 54-kDa vacuolar H(+)-ATPase subunit required for activity but not assembly of the enzyme complex in Saccharomycescerevisiae. J Biol Chem 268: 18286\u00e2\u0080\u009318292.","DOI":"10.1016\/S0021-9258(17)46842-6"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB24","unstructured":"Inoue T , Wilkens S & Forgac M (2003) Subunit structure, function, and arrangement in the yeast and coated vesicle V-ATPases. J Bioenerg Biomembr 35: 291\u00e2\u0080\u0093299."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB5","unstructured":"Kabelitz N , Santos PM & Heipieper HJ (2003) Effect of aliphatic alcohols on growth and degree of saturation of membrane lipids in Acinetobacter calcoaceticus. FEMS Microbiol Lett 220: 223\u00e2\u0080\u0093227."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB29","doi-asserted-by":"crossref","unstructured":"Kim Y , Chattopadhyay S , Locke S & Pearce DA (2005) Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomycescerevisiae. Eukaryot Cell 4: 281\u00e2\u0080\u0093288.","DOI":"10.1128\/EC.4.2.281-288.2005"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB26","doi-asserted-by":"crossref","unstructured":"Malkus P , Graham LA , Stevens TH & Schekman R (2004) Role of Vma21p in assembly and transport of the yeast vacuolar ATPase. Mol Biol Cell 15: 5075\u00e2\u0080\u00935091.","DOI":"10.1091\/mbc.e04-06-0514"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB13","doi-asserted-by":"crossref","unstructured":"Mollapour M , Fong D , Balakrishnan K , Harris N , Thompson S , Schuller C , Kuchler K & Piper PW (2004) Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast 21: 927\u00e2\u0080\u0093946.","DOI":"10.1002\/yea.1141"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB19","unstructured":"Moriya H & Isono K (1999) Analysis of genetic interactions between DHH1, SSD1 and ELM1 indicates their involvement in cellular morphology determination in Saccharomycescerevisiae. Yeast 15: 481\u00e2\u0080\u0093496."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB21","unstructured":"Munn AL & Riezman H (1994) Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes. J Cell Biol 127: 373\u00e2\u0080\u0093386."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB16","unstructured":"Park EC & Szostak JW (1992) ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity. EMBO J 11: 2087\u00e2\u0080\u00932093."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB30","doi-asserted-by":"crossref","unstructured":"Piper PW (1995) The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap. FEMS Microbiol Lett 134: 121\u00e2\u0080\u0093127.","DOI":"10.1111\/j.1574-6968.1995.tb07925.x"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB17","unstructured":"Polevoda B , Norbeck J , Takakura H , Blomberg A & Sherman F (1999) Identification and specificities of N-terminal acetyltransferases from Saccharomycescerevisiae. EMBO J 18: 6155\u00e2\u0080\u00936168."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB4","doi-asserted-by":"crossref","unstructured":"Ramos JL , Duque E , Gallegos MT , Godoy P , Ramos-Gonzalez MI , Rojasm A. , Teran W & Segura A (2002) Mechanisms of solvent tolerance in gram-negative bacteria. Annu Rev Microbiol 56: 743\u00e2\u0080\u0093768.","DOI":"10.1146\/annurev.micro.56.012302.161038"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB27","unstructured":"Rosa MF & Sa-Correia I (1996) Intracellular acidification does not account for inhibition of Saccharomycescerevisiae growth in the presence of ethanol. FEMS Microbiol Lett 135: 271\u00e2\u0080\u0093274."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB1","unstructured":"Salter GJ & Kell DB (1995) Solvent selection for whole cell biotransformations in organic media. Crit Rev Biotechnol 15: 139\u00e2\u0080\u0093177."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB25","unstructured":"Shao E & Forgac M (2004) Involvement of the nonhomologous region of subunit A of the yeast V-ATPase in coupling and in vivo dissociation. J Biol Chem 279: 48663\u00e2\u0080\u009348670."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB11","doi-asserted-by":"crossref","unstructured":"Shoemaker DD , Lashkari DA , Morris D , Mittmann M & Davis RW (1996) Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy. Nat Genet 14: 450\u00e2\u0080\u0093456.","DOI":"10.1038\/ng1296-450"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB3","doi-asserted-by":"crossref","unstructured":"Sikkema J , de Bont JA & Poolman B (1995) Mechanisms of membrane toxicity of hydrocarbons. Microbiol Rev 59: 201\u00e2\u0080\u0093222.","DOI":"10.1128\/MMBR.59.2.201-222.1995"},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB20","unstructured":"Stevens TH & Forgac M (1997) Structure, function and regulation of the vacuolar (H+)-ATPase. Annu Rev Cell Dev Biol 13: 779\u00e2\u0080\u0093808."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB9","unstructured":"Takahashi T , Shimoi H & Ito K (2001) Identification of genes required for growth under ethanol stress using transposon mutagenesis in Saccharomycescerevisiae. Mol Genet Genomics 265: 1112\u00e2\u0080\u00931119."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB2","unstructured":"Weber FJ & de Bont JA (1996) Adaptation mechanisms of microorganisms to the toxic effects of organic solvents on membranes. Biochim Biophys Acta 1286: 225\u00e2\u0080\u0093245."},{"key":"10.1111\/j.1567-1364.2006.00040.x-BIB7","unstructured":"You KM , Rosenfield CL & Knipple DC (2003) Ethanol tolerance in the yeast Saccharomycescerevisiae is dependent on cellular oleic acid content. Appl Environ Microbiol 69: 1499\u00e2\u0080\u00931503."}],"container-title":["FEMS Yeast Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/femsyr\/article-pdf\/6\/5\/744\/18016959\/6-5-744.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T12:05:45Z","timestamp":1627041945000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsyr\/article-lookup\/doi\/10.1111\/j.1567-1364.2006.00040.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,8]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1567-1364.2006.00040.x","relation":{},"ISSN":["1567-1356","1567-1364"],"issn-type":[{"value":"1567-1356","type":"print"},{"value":"1567-1364","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8]]}}}