{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:05:05Z","timestamp":1788185105335,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T00:00:00Z","timestamp":1351468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cellular Molecular Medi"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Telocytes (<jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s), a novel type of interstitial cells, were recently described in the interstitial space of tissues (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.telocytes.com\">www.telocytes.com<\/jats:ext-link>). Telocytes <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s have several very long, moniliform extensions, namely telopodes (Tps). However, the functional role(s) of <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>s is not yet understood. Successive photomicrographs of ultrathin sections were concatenated to capture the entire length of Tps which usually measure tens to hundreds of micrometres. Besides the podoms (dilations) and podomers (thin segments), ultrastructural features of Tps include the dichotomous branching and establishing homo\u2010 and heterocellular contacts. Telopodes make a labyrinthine system by 3D convolution and overlapping, their number being roughly estimated at approximately 20 per 1000\u00a0\u03bcm<jats:sup>2<\/jats:sup>. Moreover, the presence of extracellular vesicles (shedding vesicles\/exosomes) along the Tps suggests an active intercellular signalling (micro\u2010 and macromolecules), with possible significance in regulating uterine contractility.<\/jats:p>","DOI":"10.1111\/j.1582-4934.2012.01651.x","type":"journal-article","created":{"date-parts":[[2012,9,26]],"date-time":"2012-09-26T16:57:29Z","timestamp":1348678649000},"page":"2844-2849","source":"Crossref","is-referenced-by-count":100,"title":["Human myometrium \u2013 the ultrastructural 3D network of telocytes"],"prefix":"10.1111","volume":"16","author":[{"given":"Sanda M.","family":"Cre\u0163oiu","sequence":"first","affiliation":[{"name":"Division of Cellular and Molecular Medicine Department of Morphological Sciences Carol Davila University of Medicine and Pharmacy Bucharest Romania"},{"name":"Department of Ultrastructural Pathology Victor Babe\u015f National Institute of Pathology Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragos","family":"Cre\u0163oiu","sequence":"additional","affiliation":[{"name":"Division of Cellular and Molecular Medicine Department of Morphological Sciences Carol Davila University of Medicine and Pharmacy Bucharest Romania"},{"name":"Molecular Medicine Department Victor Babe\u015f National Institute of Pathology Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurentiu M.","family":"Popescu","sequence":"additional","affiliation":[{"name":"Division of Advanced Studies Victor Babe\u015f National Institute of Pathology Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2010.01059.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000319467"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-012-1333-8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2005.tb00366.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2006.06.068"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.107.066373"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1556\/APhysiol.98.2011.3.10"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2009.00894.x"},{"key":"e_1_2_7_10_1","first-page":"1067","article-title":"Telocytes, a distinct type of cell among the stromal cells present in the lamina propria of jejunum","volume":"27","author":"Cretoiu D","year":"2012","journal-title":"Histol Histopathol"},{"key":"e_1_2_7_11_1","unstructured":"CretoiuSM CretoiuD SimionescuAA PopescuLM.Telocytes in human fallopian tube and uterus express estrogen and progesterone receptors. 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